نتایج جستجو برای: amyloid beta

تعداد نتایج: 215549  

Journal: :مجله علوم اعصاب شفای خاتم 0
zeinab sadat hosseini islamic azad university, mashhad branch, mashhad, iran nikoo saeedi member of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

neurological inflammatory diseases are developing rapidly. different factors involved in the pathogenesis of these diseases. in this article, we discuss some of the mechanisms are dealt with. an aberrant procedure of beta-amyloid precursor protein (bapp) to form neurotoxic beta-amyloid peptides and an accumulated insoluble polymer of beta –amyloid (ba) that forms the senile plaque. the above pr...

Journal: :مجله دانشگاه علوم پزشکی ایلام 0
مسعود سهیلی کاشانی m sohaili kashani محمود سلامی m salami مصطفی رضایی طاویرانی m rezaee tavirani محمدرضا کفاشیان mr kafashian

introduction: one of the most common markers in alzheimer’s disease (ad) is amyloid beta (aβ) plaques. anti-inflamm-atory agents including phagocytosis by immune cells, proteolytic enzymes and liver are known to decline the risk of aβ plaques formation. in the previous study we showed that aqueous extract of lavandula angusti-folia (lavender) improved memory deficits in alzheimeric rats. here, ...

Journal: :مجله علوم اعصاب شفای خاتم 0
mohammad javad imen islamic azad university, mashhad branch, medicine faculty, mashhad, iran reza bayattork islamic azad university, mashhad branch, medicine faculty, mashhad, iran

alzheimer disease (ad) is a neurodegenerative disorder marked by cognitive and behavioral impairment. amyloid beta (aβ) peptides are involved in ad as the main component of amyloid plaques found in the brain. recent in vivo and in vitro studies have shown that there is a lot of substances that alter aβ pathogenesis of ad. aβ induces toxicity lead to increasing ros. in the other hand, 5-ht6 and ...

Journal: :مجله علوم اعصاب شفای خاتم 0
niloofar imani neuroscience department, mashhad university of medical sciences, mashhad, iran

alzheimer’s disease (ad) is a neurodegenerative disease that is the most common type of dementia.ad includes 60_80% of dementia and most people with ad have more than 65 years old.ad causes losing neuronal activity by abnormal proteins. plaques of beta-amyloid and tangles of “tau” protein can lead to ad. recently evidence has found that ad may come from outside of central nervous system (cns) a...

Journal: :avicenna journal of neuro psycho physiology 0
soheila madadi department of anatomy, faculty of medicine, iran university of medical sciences, tehran, ir iran mehdi mehdizaded cellular and molecular research center, department of anatomical sciences, faculty of advanced technology in medicine, iran university of medical sciences, tehran, ir iran; cellular and molecular research center, department of anatomical sciences, faculty of advanced technology in medicine, iran university of medical sciences, tehran, ir iran. tel/fax: +98-21-886622689

بلوچ نژاد مجرد, تورانداخت, روغنی, مهرداد, کاظملو, پرستو,

Background and Objective: Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases and results from the extracellular accumulation of b-amyloid peptides and the resulting neuronal dysfunction. In this study, the role of nicotinic acetylcholine receptors, protein kinase B (PKB) and protein kinase M (PKM) were evaluated in order to examine the mechanism of the protective effe...

ژورنال: دانشور پزشکی 2019
Amiri, Mona , Ardebili, Mehrdad Eftekhar, Baluchnejadmojarad, Tourandokht , Mehrabi, Jila ,

Background and Objective: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, in which cortical and hippocampus neurons death is the main target of neurodegeneration. In addition to extracellular beta amyloid accumulation and the production of neural tangles, one of effective factors in the pathology of Alzheimer's disease is vascular injury in the elderly including disturbanc...

Journal: :مجله علوم اعصاب شفای خاتم 0
mahboobeh paporaki islamic azad university, mashhad branch, mashhad, iran zeinab sadat hosseini islamic azad university, mashhad branch, mashhad, iran fatemeh razmi islamic azad university, mashhad branch, mashhad, iran fatima sadat zojaji islamic azad university, mashhad branch, mashhad, iran

platelet aggregation beta amyloid main causes inflammation of neurons in alzheimer’s disease. in fact, creating this inflammation due to inappropriate actions in blood brain barrier (bbb) and astrocyte and microglia during the last century that studies conducted in this case nothing has been found. the only thing that can be done to prevent and reduce pro-inflammatory factors such as cytokines ...

Mohsen Mahdinejad Kashani, Saman Esmaeilnejad, Sepideh Mansoori Majoofardi,

Alzheimer's desease is the most common age-related neurodegenerative disorder, and cognitive problems such as defects in learning and memory are of its symptoms.  Among the factors involved in the pathogenesis of the disease are biochemical disorders in protein production, oxidative stress, decreased acetylcholine secretion and inflammation of the brain tissue. Extra-neuronal accumulation ...

Fatemeh Razmi, Fatima Sadat Zojaji, Mahboobeh Paporaki, Zeinab Sadat Hosseini,

Platelet aggregation beta amyloid main causes inflammation of neurons in Alzheimer’s disease. In fact, creating this inflammation due to inappropriate actions in blood brain barrier (BBB) and astrocyte and microglia during the last century that studies conducted in this case nothing has been found. The only thing that can be done to prevent and reduce pro-inflammatory factors such as cyto...

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