نتایج جستجو برای: and irs
تعداد نتایج: 16828019 فیلتر نتایج به سال:
b a ckground: malaria still is considered as a public health problem in iran. the aim of the national malaria control department is to reach the elimination by 2024. by decreasing the number of malaria cases in preelimination phase the cost effectiveness of malaria interventions decreases considerably. this study estimated the cost effectiveness of various strategies to combat malaria in preeli...
the zagros forests (west of iran) have been highly exploited in recent decades by human impacts. easy access, abundance and variety of valuable forest yields have led to population growth density, creation of new residential areas and deforestation activities. in order to determinate the distribution and rate of deforestation from 1995 to 2006 by using the satellite imagery (irs-1c and landsat...
Although we and others have generated IRS-2 knock-out (IRS-2(-/-)) mice, significant differences were seen between the two lines of IRS-2(-/-) mice in the severity of diabetes and alterations of beta-cell mass. It has been reported that although IRS-1 and IRS-3 knock-out mice showed normal blood glucose levels, IRS-1/IRS-3 double knock-out mice exhibited marked hyperglycemia. Thus, IRS-1 and IR...
To investigate the role of insulin receptor substrate 1 (IRS-1) and IRS-2, the two ubiquitously expressed IRS proteins, in adipocyte differentiation, we established embryonic fibroblast cells with four different genotypes, i.e., wild-type, IRS-1 deficient (IRS-1(-/-)), IRS-2 deficient (IRS-2(-/-)), and IRS-1 IRS-2 double deficient (IRS-1(-/-) IRS-2(-/-)), from mouse embryos of the corresponding...
Insulin promotes adipocyte differentiation via a complex signaling network involving multiple insulin receptor substrates (IRSs). In cultured brown preadipocytes, expression of IRS-1 and IRS-2 mRNAs and proteins was at relatively high levels before and after differentiation into mature fat cells, while IRS-3 transcript was not detectable in preadipocytes but increased during the course of diffe...
BACKGROUND Insulin resistance is associated with atherosclerosis, but its mechanism is unknown. It has been reported that insulin receptor substrate (IRS)-1 deficient (IRS-1-/-) mice showed insulin resistance without type 2 diabetes, whereas the IRS-2 deficient (IRS-2-/-) mice showed insulin resistance with type 2 diabetes. METHODS AND RESULTS We investigated neointima formation in the IRS-1-...
In this paper, we explore the impacts of utilizing intelligent reflecting surfaces (IRS) in a power-splitting based simultaneous wireless information and power transfer (PS-SWIPT) system and compare its performance with the traditional decode and forward relaying system. To analyze a more practical system, it is also assumed that the receiving nodes are subject to decoding cost, and they are on...
BACKGROUND Increasing evidence suggests that miR-126 participates in the glucose homeostasis through its target molecules. Although bioinformatics analysis predicts that miR-126 can bind with the insulin receptor substrate-2(IRS-2) mRNA at the "seed sequence", but there are still no definitely reports to support it. In this study, we provided evidences that IRS-2 was one of the target genes of ...
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