conclusions the at1r a1166c polymorphism appeared not to be associated with the presence of acs in the population studied. background there are very limited data for iranian populations on the predisposing genetic factors for acute coronary syndrome (acs). results there was no statistical difference in the genotype frequency of patients and healthy subjects with regard to age and gender (p > 0....

introduction: renin angiotensin system has an important role in blood pressure and renal functions. active angiotensin-converting enzyme 2 converts angiotensin i into angiotensin-(1-7) which is a vasodilator hormone and interacts with nitric oxide changes as well as other angiotensin ii receptors. in this study we evaluated the role of mas receptor antagonist (a779) and renal perfusion pressure...

Background: Angiotensin converting enzyme (ACE) upregulation in stromal cells of joints affected by rheumatoid arthritis may lead to higher tissue angiotensin II that is a vasoconstrictor and mitogen factor. To date, the role of angiotensin II on regulating blood flow in inflamed joints has not been studied. Methods: Acute and chronic joint inflammation was induced in rabbits by intra-articular...

stroke is the leading cause of death and disability in the world after the cancer and cardiovascular diseases. genetic factors have main significance to got stroke. renin-angiotensin system contains candidate genes and polymorphisms for causing stroke. there are reported associations between stroke and angiotensin ii type-1 receptor g. 1166a > c polymorphism (rs5186). therefore in this study th...

Introduction: Renin angiotensin system has an important role in blood pressure and renal functions. Active angiotensin-converting enzyme 2 converts angiotensin I into angiotensin-(1-7) which is a vasodilator hormone and interacts with nitric oxide changes as well as other angiotensin II receptors. In this study we evaluated the role of Mas receptor antagonist (A779) and renal perfusion press...

background: angiotensin converting enzyme (ace) upregulation in stromal cells of joints affected by rheumatoid arthritis may lead to higher tissue angiotensin ii that is a vasoconstrictor and mitogen factor. to date, the role of angiotensin ii on regulating blood flow in inflamed joints has not been studied.   methods: acute and chronic joint inflammation was induced in rabbits by intra-articul...

Background: The vascular function of Angiotensin II-type-2 receptors in adults is controversial. We sought their location and function in mouse aortic rings at young and old mice. Materials and Methods: Male C57Bl mice (aged 4 and 14 months) were killed by CO2. The descending thoracic aorta was cleaned and dissected into rings. Aortic rings were mounted in Krebs’ solution at 37 °C an...

background: the vascular function of angiotensin ii-type-2 receptors in adults is controversial. we sought their location and function in mouse aortic rings at young and old mice. materials and methods: male c57bl mice (aged 4 and 14 months) were killed by co2. the descending thoracic aorta was cleaned and dissected into rings. aortic rings were mounted in krebs’ solution at 37 °c and then setu...