helminths infections are chronic illness in human being and cattle. the use of alternate drugs has been a remedial measure against the resistant strains of helminth parasites, as well as means of reducing the cost of controlling diseases caused by helminthes. pseudocedrelakotschyi is a medicinally valuable plant and possesses various pharmacological properties. p. kotschyi has been traditionall...

Helminths infections are chronic illness in human being and cattle. The use of alternate drugs has been a remedial measure against the resistant strains of helminth parasites, as well as means of reducing the cost of controlling diseases caused by helminthes. Pseudocedrelakotschyi is a medicinally valuable plant and possesses various pharmacological properties. P. kotschyi has been traditionall...

Levamisole, an anthelminthic agent with immunostimulatory properties, does not alter in vitro macrophage-lymphocyte rosette formation between sheep alveolar macrophages and autochthonous lymphocytes.

Echinococcus multilocularis, the causative agent of zoonotic alveolar echinococcosis, can be controlled effectively by the experimental delivery of anthelminthic baits for urban foxes. Monthly baiting over a 45-month period was effective for long-lasting control. Trimonthly baiting intervals were far less effective and did not prevent parasite recovery.

Objective: To evaluate the anthelmintic activity of Artemisia indica. Methods: In the present investigation, the in vitro anthelminthic activity of chloroform, methanol and aqueous extracts of Artemisia indica was carried out against Indian adult earthworm Pheretima posthuma. Piperazine citrate was used as the standard reference. Five different concentrations (1.25, 2.5, 3.75, 5.0 and 6.25 mg/m...

Ethanolic and aqueous extracts of Bambusa vulgaris leaf were comparatively screened for anthelmintic activities; ethanolic extract appeared to be more potent in expelling the ova of Ascaris worm and the treated rabbits showed rapid weight gain with a mean value of 0.25kg after treatment as against 0.21g during infection than aqueous extracts. These suggest that they could serve as an alternativ...

Albendazole is a clinically important anthelminthic agent known to have variable and low oral bioavailability. The aim of this work was to determine whether albendazole, a CYP3A4 substrate, is also a substrate for the multidrug efflux transporter P-glycoprotein. Both in vitro and in vivo methods were used to assess the role of P-glycoprotein-mediated albendazole transport. In cultured LLC-PK1, ...

A double-blind clinical trial was conducted among 9- to 11-year-old children in sixteen schools in the Chon Buri province of Thailand to assess the effects of an iron supplement combined with an anthelminthic agent (i.e. albendazole). In addition to the albendazole, Fe or placebo tablets were distributed to 2268 children enrolled in grades three to five without knowledge of the Fe status of the...

Helminthiasis or infection with gastrointestinal nematodes such as Haemonchus contortus is a common problem in grazing animals which can lead to poor animal performance and economic loss to the livestock industry (Waller & Thamsborg, 2004). In Malaysia, the main methods of controlling gastrointestinal nematodes is using chemical anti-parasitic drug or anthelmintic and also by maintaining good p...

This review discusses the landmark anthelminthic substances – traditional medicine components, different categories of pluripotential synthetic and naturally occurring compounds. Much attention is paid to the sections devoted to recent discoveries (Emodepside, Monepantel, Derquantel, Tribendimidine) and to some promising works. The review is also focused on some aspects of molecular mechanisms ...