Dental caries is a disease caused by Streptococcus mutans. The use of chlorhexidine to inhibit bacterial colonization has side effects such as tooth staining and can kill the normal flora when used long term. Epigallocatechin gallate (EGCG) chemical compound in form polyphenols from green tea catechins which have antimicrobial potency microorganism growth biofilm formation. Type Laboratory Expe...

abstract microbial contaminants transport to groundwater is a serious environmental problem that can result in large outbreaks of waterborne diseases. some of bacteria can travel from vadose zone and cause contamination of groundwater resources. thus, an accurate prediction of transport and fate of pathogenic microorganisms in unsaturated soil is needed to protect groundwater resources. the mai...

Staphylococcus aureus is aerobic bacteria that are gram-positive and one of the normal human flora on skin mucous membranes. Most infections in oral cavity caused by aureus, which a can turn into pathogen if trauma or abrasion occurs mucosal surface. Jengkol peel thought to contain tannin compounds, have potential as an anti-inflammatory, anti-diarrheal, antioxidant, treatment mouth, burns. Thi...

The Type VI secretion system is a widespread bacterial nanomachine, used to deliver toxins directly into eukaryotic or prokaryotic target cells. These secreted toxins, or effectors, act on diverse cellular targets, and their action provides the attacking bacterial cell with a significant fitness advantage, either against rival bacteria or eukaryotic host organisms. In this review, we discuss th...

Mammalian cells deploy autophagy to defend their cytosol against bacterial invaders. Anti-bacterial autophagy relies on the core autophagy machinery, cargo receptors, and "eat-me" signals such as galectin-8 and ubiquitin that label bacteria as autophagy cargo. Anti-bacterial autophagy also requires the kinase TBK1, whose role in autophagy has remained enigmatic. Here we show that recruitment of...

The alarming increase in drug-resistant bacteria makes a search for novel means of fighting bacterial infections imperative. An attractive approach is the use of agents that interfere with the ability of the bacteria to adhere to tissues of the host, since such adhesion is one of the initial stages of the infectious process. The validity of this approach has been unequivocally demonstrated in e...

Naturally fermented soybean foods have anti-thrombotic properties due to the presence of microbial fibrinolytic enzymes. However, enzyme-producing bacteria from naturally Eastern Himalayas viz. kinema, grep-chhurpi, peha, peron namsing, peruñyaan and bemerthu not been screened yet. Therefore, this study aims screen these also assess their therapeutic such as antioxidant, anti-inflammatory, flav...