–A novel series of 2-phenyl-5-sulpha/substituted-3-phenyl substituted azo indoles have been synthesized and tested as an antifertility activity in mature albino mice. The tested compounds showed significant antifertility activity. Keywords––Synthesis, Antifertility activity, Indore, Azo indoles, chemical analysis.

To evaluate antifertility mode of action of extracts of Juniperus communis Linn., its various extracts were investigated for estrogenic, antiestrogenic, progestagenic and antiprogestagenic properties in laboratory animals. Investigations reveal that the extract possessed only antiprogestational activity which accounts for its antifertility effect.

The aim of this review was to provide a comprehensive summary of medicinal plants used as antifertility agents in females throughout the world by various tribes and ethnic groups. We undertook an extensive bibliographic review by analyzing classical text books and peer reviewed papers, and further consulting well accepted worldwide scientific databases. We performed CENTRAL, Embase, and PubMed ...

Results of past animal studies have indicated the antifertility effects of phthalate esters and additional studies have suggested the potential mutagenic effects at very high doses. A toxicity study in mice has also been conducted in which chronic LD50 values were calculated for a group of phthalate esters. For DEHP, for example, the acute LD50 was 38.35 ml/kg, but after 10 weeks the value fell...

Fertility is possibly the most important capability contained within living cells or species. Therefore, finding the most efficacious way to enhance or promote fertility is the main goal of all living things. To best manage nature's strong predisposition for fertility, plant-based traditional medicines for birth control have long been incorporated into medical practices throughout the world, in...

the discovery of the antifertility activity of gossypol led scientists and researchers to the development of compounds with antifertility activity that can be used as male contraceptives. these studies resulted in discovery of the antifertility activity of several classes of compounds which have been reported in the literature. this article deals with the synthesis of four new analogues of pyri...

Alcoholic extract of Acacia leucophploea root was investigated to find out their antifertility activity. Antifertility activity was evaluated by estrus cycle study, genital organ weight and biochemical parameter. Alcoholic extract at 200 mg/kg dose increased proestrus phase significantly while estrus and metaestrus phases were decreased. At this dose weight of ovary also decreased and cholester...

The discovery of the antifertility activity of gossypol led scientists and researchers to the development of compounds with antifertility activity that can be used as male contraceptives. These studies resulted in discovery of the antifertility activity of several classes of compounds which have been reported in the literature. This article deals with the synthesis of four new analogues of pyri...

Medicinal plants play a key role in human life as they are helpful in curing several diseases. They not only support health by the pharmacological nature but also utilizable as contraceptive options. The present study reveals that the medicinal plants Melia azedarach and Dodonaea viscosa leaf extracts showing antifertility activity. The decreased sperm count and reproductive organ weights inclu...

Evaluation of herbs for antifertility effects has been in progress worldwide for several decades to identify effective and safe substances for control of population explosion. Inspite of availability of internationally accepted guidelines for the assessment of reproductive toxicity/antifertility potential of test substances, many published articles, on critical review, seem to lack reproducibil...