An interim update of the chapter titled Pharmacologic Management of Type 2 Diabetes in the 2013 Clinical Practice Guidelines was recently published in Canadian Journal of Diabetes; it incorporates the sodium glucose linked transporter 2 (SGLT2) inhibitor class (1). Since the publication of the update, another SGLT2 inhibitor has received notice of compliance from Health Canada (2). The article’...

The quinoline core structure is an important heterocyclic feature that can be found in numerous biologically active componds which exhibit a vast range of pharmacological properties such as antimalarial [1], antibacterial [2], antimicrobial [3], and antistaphylococcal activities [4]. Meanwhile, an important class of antibiotics possesses a 4-quinolone framework in their structure [5], and also ...

Banana has been widely cultivated. This study aimed to determine the antihyperglycemic activity of Uli banana leaves infusion. The was evaluated by oral glucose and sucrose tolerance test. A bolus sugar given after infusion blood sampled at 0, 15, 30, 60, 90 120 minutes for analyses. trapezoidal rule used area under curve (AUC) glucose. Infusion 3.3 g/kg showed a significant decrease AUC (p<...

The aim of this study was to investigate the effects of ethanolic extract of the whole plant of Phyllanthus rheedii wight P.rheedii as antihyperglycemic, antihyperlipidemic and antioxidant effect in streptozotocin (STZ) induced diabetic rats. Male Wistar rats were administered P.rheedii (250 mg/kg) orally for 21 days and blood glucose level was measured weekly. At the end of 21 days, the serum ...

Plants with hypoglycemic properties are important in the treatment of diabetes. One of the mechanisms in reducing blood glucose is preventing the digestive absorption of glucose. The aim of this study was to evaluate the antioxidant properties of some traditional medicinal plants collected from different regions of Iran and their effects on glucose diffusion decrease. The amounts of phenolic co...