The type I interferon system plays a critical role in limiting the spread of viral infection. Viruses induce the production of interferon (IFN), which after binding to the IFN-α/β receptor (IFNAR), and triggering of the JAK/STAT signaling cascade, results in the induction of interferon-stimulated genes (ISGs). These ISGs function to inhibit viral replication and to regulate the host immune resp...

Background: Cumin (Cuminum cyminum L. [family Apiaceae]) seed essential oil is reported to have antiseptic activity. Until now the antiviral properties of cumin seed extracts on viruses such as herpes simplex virus-1 (HSV-1) have not been studied. The objective of this study was to investigate the in vitro effects of aqueous, methanolic and hydroalcoholic extracts of cumin seed on HSV-1 growth ...

background: cumin ( cuminum cyminum l . [family apiaceae]) seed essential oil is reported to have antiseptic activity. until now the antiviral properties of cumin seed extracts on viruses such as herpes simplex virus-1 (hsv-1) have not been studied. the objective of this study was to investigate the in vitro effects of aqueous, methanolic and hydroalcoholic extracts of cumin seed on hsv-1 growt...

The synthesis of the title compound, bitamycin, by means of BU4NF is described. This new antiviral drug was found to be one of the most powerful and least toxic substances for antiviral therapy in man. The physical and chemical behavior as well as the antiviral activities and clinical properties of this compound were found to be significantly different from that reported by Schaeffer, et a...

the synthesis of the title compound, bitamycin, by means of bu4nf is described. this new antiviral drug was found to be one of the most powerful and least toxic substances for antiviral therapy in man. the physical and chemical behavior as well as the antiviral activities and clinical properties of this compound were found to be significantly different from that reported by schaeffer, et al. al...