نتایج جستجو برای: apoptosi
تعداد نتایج: 5 فیلتر نتایج به سال:
FADD/MORT1 is a death domain (DD)-containing adapter/signaling moleculethat interactswith the intracellularDD of FAS/APO-I (CD95) and tumor necrosisfactor receptor1 and the prodomainof caspase-8 (MchS/MACH/FLICE). FADD engagementof caspase-8presumably ac tivates this caspaseand leadsto apoptosi&Another DD-containing adap tsr/signaling molecule,CRADD, wasIdentified and wasshown to induce apoptos...
background: acute promyelocytic leukemia is a sub-type of acute myelogenous leukemia that occurs in about 10-15% of patients with aml. approximately 20%-30% of these patients, who are treated with the current standard all trans retinoic acid (atra) and anthracyclin-based chemotherapy regimen, suffer relapse in less than a year. arsenic trioxide (ato) as a single agent can induce complete remiss...
Netropsin, an antitumor/antiviral antibiotic, binds to cellular DNA in the minor groove of the double helix. Minor groove drugs have the ability to act as (i) DNA sequence recognition agents and (ii) modifiers of protein-DNA function. The use of antitumoral antibiotics in the radiotherapy of tumor determines a special interest in the behavior of these ligands during the -irradiation of the cell...
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