The case of a 44-year-old woman is reported. The diagnosis after the appropriate tests and laparotomy was ACTH-secreting 'apudoma' of the gallbladder. This is a rare tumour and this case is believed to be the first reported of an ectopic hormone producing tumour from this side.

A 9 year old girl underwent laparotomy because of intermittent diarrhoea, present since infancy. Histology of a mass at the head of pancreas and multiple hepatic nodules suggested an apudoma. Plasma serotonin and urinary excretion of 5 hydroxy indole acetic acid were raised. The child is asymptomatic four years after diagnosis.

A: angiography; US: ultrasonography; EUS: endoscopic ultrasonography; IUS: intraoperative ultrasonography; EUS-FNA: endoscopic ultrasonography-guided fine-needle aspiration; MRI: magnetic resonance imaging; SRS: octreoscan; CT: computerized tomography; MDCT: multidetector computerized tomography; PET: positron emission tomography; PET-CT: PET with computerized tomography; ICC: immunocytochemist...

Two patients have been studied with a two and a half and nine year history of metastatic pancreatic apudoma. In both patients the main feature was chronic watery diarrhoea with remissions after partial tumour resection and streptozotocin therapy. Plasma levels of circulating VIP and neurotensin were persistently raised in both patients. Chromatographic analysis of the plasma showed that a signi...

in this study, l-131-mibg imaging was performed in 44 patients with clinical suspicion of tumors originating from neuro-endocrine system. the patients were referred to our department following plasma and urinary measurement of epinephrine, norepinehrine and vanilmandelic acidfvma). radionuclide imaging was performel as a comparative or confirmatory measure in all patients who had previous abdom...