In the present study, we established an injury model of the mouse carotid artery. Complete removal of the endothelium was achieved with a flexible wire. A platelet monolayer covered the denuded surface, and damage to underlying medial smooth muscle cells (SMCs) was detected. Injection of [3H]thymidine was used to determine the replication index for medial SMCs, which was found to be 1.6% at 2 d...

Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth muscle cells, the effects of mebendazole on vascular smooth muscle cell proliferation were tested in vitro and in a mouse model of arterial injury. ...

Objective- To evaluate the effects of venesection and vitamin C on systemic renal and hepatic lesions after limb ischemia-reperfusion in rabbit. Design- Experimental study. Animals- 20 male white New Zealand rabbits between 2.5-3 kg, randomly assigned in 5 equal groups. Procedures- After general anesthesia right femoral artery and vein were approached from inguinal region. In treatment and c...

BACKGROUND Though retrograde neuronal death and vascular insufficiency have been well established in plegics following intracerebral hemorrhage, the effects of plegia on arterial nervorums of peripheral nerves have not been reported. In this study, the histopathological effects of the intracerebral hemorrhage on the dorsal root ganglions and sciatic nerves via affecting the arterial nervorums w...

PURPOSE We sought to analyze the results of arterial injury management in a busy metropolitan vascular unit and risk factors associated with mortality and morbidity. PATIENTS AND METHODS We analyzed 120 patient with arterial injury treated between year 2000 and 2010 at the University Clinical Center of Kosovo. Seven of these years were prospective and three retrospective study. RESULTS The ...

A 21-year-old male presented to our hospital for life-threatening pelvic fracture, mandating emergent transarterial embolization of the right internal pudendal artery. At five-month post-injury, penile arterial flow was severely impaired, thus revascularization surgery were planned, before attempting urethroplasty a 2-cm gap in posterior urethra. However, reevaluation angiography results obtain...

BACKGROUND Postoperative myocardial injury occurs frequently after noncardiac surgery and is strongly associated with mortality. Intraoperative hypotension (IOH) is hypothesized to be a possible cause. The aim of this study was to determine the association between IOH and postoperative myocardial injury. METHODS This cohort study included 890 consecutive patients aged 60 yr or older undergoin...

OBJECTIVE To evaluate the feasibility and effectiveness of endovascular repair for blunt popliteal arterial injuries. MATERIALS AND METHODS A retrospective analysis of seven patients with clinical suspicion of popliteal arterial injuries that were confirmed by arteriography was performed from September 2009 to July 2014. Clinical data included demographics, mechanism of injury, type of injury...

conclusions: the effects of propofol on hemodynamics and arterial oxygen pressure during one- or two-lung ventilation were not different from those of isoflurane. results: sixty patients (mean age = 4124.18 ± 18.63 years) were divided into two groups. the age and gender of the subjects were not statistically different between the two groups. in the propofol group, the arterial oxygen pressure d...