نتایج جستجو برای: association study
تعداد نتایج: 4251989 فیلتر نتایج به سال:
testing plays a vital role in any language teaching program. it allows teachers and stakeholders, including program administrators, parents, admissions officers and prospective employers to be assured that the learners are progressing according to an accepted standard (douglas, 2010). the problems currently facing language testers have both practical and theoretical implications but the first i...
schizophrenia is a complex disorder with polygenic inheritance. the mthfr gene (omim: 607093) plays an important role in the folate metabolism. it has been suggested that c677t (rs1801133) and a1298c (rs1801131) genetic polymorphisms in the mthfr gene lead to the decreased activity of the methylenetetrahydrofolate reductase enzyme which may have significant effect on developing schizophrenia. w...
Genome-wide association studies (GWAS) have quickly become the norm in dissecting the genetic basis of complex diseases. Family-based association approaches have the advantages of being robust to possible hidden population structure in samples. Most of these methods were developed with limited markers. Their applicability and performance for GWAS need to be examined. In this report, we evaluate...
this study investigates the relationships between iranian efl teachers’ perfectionism, burnout and their teaching style preferences, and also the difference between male and female efl teachers and their teaching style preferences. to this end, a sample of 99 efl teachers (46 males and 53 females), who had years of teaching experience, were selected. the measurement scales used in this study we...
Proceedings Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses L Adrienne Cupples*, Joseph Beyene, Heike Bickeböller, E Warwick Daw, M Daniele Fallin, W James Gauderman, Saurabh Ghosh, Ellen L Goode, Elizabeth R Hauser, Anthony Hinrichs, Jack W Kent Jr, Lisa J Martin, Maria Martinez, Rosalind J Neuman, Michael Province, Silke Szymczak, Marsha A Wilcox, Andreas Z...
Currently, the genetic variants identified by genome wide association study (GWAS) generally only account for a small proportion of the total heritability for complex disease. One crucial reason is the underutilization of gene-gene joint effects commonly encountered in GWAS, which includes their main effects and co-association. However, gene-gene co-association is often customarily put into the...
We present a comprehensive toolkit for post-processing, visualization and advanced analysis of GWAS results. In the spirit of comparable tools for gene-expression analysis, we attempt to unify and simplify several procedures that are essential for the interpretation of GWAS results. This includes the generation of advanced Manhattan and regional association plots including rare variant display ...
There is growing evidence that much more of the genome than previously thought is required to explain the heritability of complex phenotypes. Recent studies have demonstrated that numerous common variants from across the genome explain portions of genetic variability, spawning various avenues of research directed at explaining the remaining heritability. This polygenic structure is also the mot...
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