Acrolein is a highly reactive alpha,beta-unsaturated aldehyde produced endogenously during lipid peroxidation and naturally distributed pervasively in living environments, posing serious threats to human health if not properly metabolized. In this study, we report aldose reductase-like-1 (ARL-1) as a novel enzyme that catalyzes the reduction of acrolein and protects cells from their toxicity. U...

In the previous two Chapters, we proposed fraction nonconforming nonparametric control charts to monitor process location and process variability. It is also shown that performance of proposed control charts are superior to that of the Shewhart X and sign charts. If process is running in an in-control state for a long period, it will reach in steady-state mode. In order to characterize long-ter...