نتایج جستجو برای: b cells
تعداد نتایج: 2069164 فیلتر نتایج به سال:
purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...
abstract background b cells play an important role in the immune system due to production of the immunoglobulin and secreting several cytokines. it has been shown that b cells produced successfully in the presence of stem cell factor (scf) and flt3 ligand (flt3l). il2, il7, and il15 cytokines as -common family have an essential cytokines may support either synergistically or in an additi...
conclusions the inhibition of tregs is a novel therapeutic approach to cure chronically hbv infected patients. however, further studies are needed to investigate the safety and efficacy of this approach. results considering the increased levels of regulatory cytokines and also regulatory t cells (tregs) during chb, it seems that these cells are deeply involved in chb infection. the inhibition o...
chronic granulomatous disease (cgd) is a rare primary immunodeficiency disorder characterized by a greatly increased susceptibility to severe fungal and bacterial infections caused by defects in nadph oxidase of phagocytic cells. we aimed to investigate immunophenotype alterations of naïve and memory b cells and b1a cells in peripheral whole blood from iranian patients with cgd. ...
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human diploid fibroblast cells produce a spectrum of necessary growth factors and extracellular matrix (ecm) components essential for growth and proliferation of a variety of other cell types. in this study, the effect of five human embryonic fibroblast cell lines, isolated from liver, lung, skin and foreskin tissues, was investigated. a coculture system analyse was employed to cloning efficien...
conclusions this study suggests that the il-7 level of chb patients may be related to tfh cells. in chb patients, il-7 possibly increases the level of tfh cells and hbv-specific cellular immune responses and thereby reduces the hbv dna level. background in patients with chronic hepatitis b (chb), the relation of interkeukin-7 (il-7) to either the t follicular helper cells (tfh cells) or to a sp...
هدف: کشت سلول های اسپرماتوگونی و تولید سلول های پر توان embryonic stem cells (es like cells) که دارای قابلیت بازسازی و تولید هرسه نوع لایه زایای جنینی می باشند، این سلول ها را به عنوان منبع کافی و جدیدی برای سلول درمانی و ترمیم در بیماریها از جمله بیماریهای نورودژنراتیو پیشنهاد می دهد. در تحقیق حاضر تمایز سلول های اسپرماتوگونی موش به سلول های شبه الیگودندروسیت و نقش آنها درمیلین سازی پس از پیون...
objectives: platelets are anucleated fragments derived from megakaryocytes. it has been demonstrated that platelets play a role in hemostasis and innate immunity. in addition, platelets have a cd40 ligand which is an important molecular marker in motivating immune cells. thus, platelets also have a role in adaptive immunity as seen by their ability to activate b cells. since human platelet micr...
Background: B cells can increase the expression of granzyme B in CD8+ T cells through 4-1BBL/4-1BB interaction and promote anti-tumor immunity. Objective: To investigate the expression of 4-1BBL on B cells in the breast tumor draining lymph nodes (TDLNs) and its association with disease parameters. Methods: Using Ficoll-Hypaque gradi...
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