A 6-week feeding experiments were carried out to determine the effects of different levels of dietary betaine on growth performance, food efficiency and survival rate of pike perch which has a critical period during transition feeding. Fingerlings of pike perch were fed with live food (treatment A), without betaine added to biomar (treatment B), 1% betaine added to biomar (treatment C) and 2% ...

Betaine is a non-essential nutrient which performs several important physiological functions in organisms. Abundant data exist to suggest that betaine has a potential for prevention of chronic diseases and that its dietary intake may contribute to overall health enhancement. Several studies have pointed out that the betaine status of the general population is inadequate and have suggested nutri...

UNLABELLED Through the use of genetic, enzymatic, metabolomic, and structural analyses, we have discovered the catabolic pathway for proline betaine, an osmoprotectant, in Paracoccus denitrificans and Rhodobacter sphaeroides. Genetic and enzymatic analyses showed that several of the key enzymes of the hydroxyproline betaine degradation pathway also function in proline betaine degradation. Metab...

Nonalcoholic fatty liver (NAFL) is a common liver disease, associated with insulin resistance. Betaine has been tested as a treatment for NAFL in animal models and in small clinical trials, with mixed results. The present study aims to determine whether betaine treatment would prevent or treat NAFL in mice and to understand how betaine reverses hepatic insulin resistance. Male mice were fed a m...

This review focuses on the metabolic and osmoregulatory functions of betaine and its impact on nutrient digestibility and performance in pigs and poultry. Betaine is the trimethyl derivative of the amino acid glycine, and is present in plant and animal tissue. It has been shown to play an important role in osmoregulation of plants, bacteria and marine organisms. Due to its chemical structure, b...

BACKGROUND Urinary betaine excretion positively correlated with plasma homocysteine in outpatients attending a lipid disorders clinic (lipid clinic study). We aimed to confirm this in subjects with established vascular disease. METHODS The correlation between betaine excretion and homocysteine was compared in samples collected from subjects 4 months after hospitalization for an acute coronary...

BACKGROUND Since betaine is an osmolyte and methyl donor, and abnormal betaine loss is common in diabetes mellitus (>20% patients), we investigated the relationship between betaine and the post-methionine load rise in homocysteine, in diabetes and control subjects. The post-methionine load test is reported to be both an independent vascular risk factor and a measure of betaine sufficiency. ME...

Myocardial infarction is commonly considered as a leading cause of cardiovascular disease taking the lives of seven million people annually. Liver dysfunction is associated with cardiac diseases. The profile of abnormal liver functions in heart failure is not clearly defined. This study was designed to investigate the protective effects of betaine on liver injury after myocardial infarction ind...

 A 6-week feeding experiments were carried out to determine the effects of different levels of dietary betaine on growth performance, food efficiency and survival rate of pike perch which has a critical period during transition feeding. Fingerlings of pike perch were fed with live food (treatment A), without betaine added to biomar (treatment B), 1% betaine added to biomar (treatment C...

1. Antioxidant and methyl donor effects of betaine in experimental animal models have recently been demonstrated. The present study was therefore designed to examine the antioxidant effects of betaine on the antioxidant status and meat quality of breast muscles in broilers. 2. Cobb broilers were randomly divided into Control, Methionine low, Methionine low plus betaine, and Betaine groups. 3. T...