OBJECTIVES/HYPOTHESIS Currently available silicone and metallic stents for tracheal stenosis are associated with problems of granulations, mucus trapping, and difficult removals. Our aim was to develop a novel bioabsorbable tracheal stent with mitomycin C (MMC) drug elution to circumvent such problems. STUDY DESIGN A randomized animal study. METHODS Twenty-five rabbits were randomly assigne...

The development of the suture anchor has played a pivotal role in the transition from open to arthroscopic techniques of the shoulder. Various suture anchors have been manufactured that help facilitate the ability to create a soft tissue to bone repair. Because of reported complications of loosening, migration, and chondral injury with metallic anchors, bioabsorbable anchors have become increas...

Orthognathic surgery requires stable fixation for uneventful healing of osteotomized bony segments and optimal remodeling. Titanium plates and screws have been accepted as the gold standard for rigid fixation in orthognathic surgery. Although titanium osteofixation is the most widely used approach, the use of bioabsorbable devices has been increasing recently. Biodegradation of bioabsorbable de...

Bioabsorbable phosphate glass fibre/polymer composites are being investigated as alternatives to commonly used metal alloy-based bone fracture fixation devices. According to Knowles [1], these ‘Third Generation’ implants remain in the body for the short term necessary for mechanical stabilisation of tissue. In addition the degradation products of the bioabsorbable implants perform an active fun...

Tendon transfer techniques in the foot and ankle are used for tendon ruptures, deformities, and instabilities. This fresh cadaver study compares the tendon fixation strength in 10 paired specimens by performing a tendon to tendon fixation technique or using 7 x 20-25 mm bioabsorbable interference-fit screw tendon fixation technique. Load at failure of the tendon to tendon fixation method averag...

BACKGROUND The ultimate goal of craniofacial reconstructive surgery is to achieve the most complete restoration of facial functions. A bioabsorbable fixation system which does not need secondary operation for implant removal has been developed in the last decade. The purpose of this study is to share the experience of authors and to demonstrate the efficacy of bioabsorbable mesh in a variety of...

Background: The incidence of placement of osteosynthetic materials has grown worldwide. Bioabsorbable materials are more commonly used now days in Orthopedic surgeries. Implants modify the risk of infection by bacterial adhesion, tissue integration, and immunomodulation. Bacterial adhesion to implant leads to interaction between bacteria and implant. Aim: To evaluate the incidence of infections...

BACKGROUND Bioabsorbable plates and screws are commonly used to reduce maxillofacial bones, particularly in pediatric patients because they degrade completely without complications after bone healing. In this study, we encountered eight cases of a delayed foreign body reaction after surgical fixation with bioabsorbable plates and screws. METHODS A total of 234 patients with a maxillofacial fr...

BACKGROUND Bioabsorbable polymer stents with drug elution only on the abluminal surface may be safer than durable polymer drug-eluting stents. OBJECTIVE To report the experimental findings with the Inspiron™ stent - a bioabsorbable polymer-coated stent with sirolimus release from the abluminal surface only, recently approved for clinical use. METHODS 45 stents were implanted in the coronary...

BACKGROUND Acute thrombogenicity and re-endothelialization represent clinically relevant end points pertaining to the safety of coronary stents, which have not been compared among biodegradable polymer-based drug-eluting metallic stents and fully bioabsorbable scaffolds to date. METHODS AND RESULTS We investigated comparative outcomes with respect to acute thrombogenicity and re-endothelializ...