The present study investigates the effect of Withania somnifera (WS), a well-known adaptogenic agent in Indian system of Medicine, on acute cerebral reperfusion and long-term cerebral hypoperfusion in rats. Acute ischemiareperfusion (30 min occlusion of bilateral common carotid arteries followed by 45 min. reperfusion) and Long-term cerebral hypoperfusion (for 15 days) in C.F. strain rats were ...

iv LIST OF ORIGINAL PUBLICATIONS v

Katarina Vučićević1, Branislava Miljković1, Sandra Vezmar Kovačević1, Zoran Todorović2, Milica Prostran2 and Iztok Grabnar3 1Department of Pharmacokinetics and Clinical Pharmacy, Faculty of Pharmacy, University of Belgrade, 2Department of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine, University of Belgrade, 3Chair of Biopharmaceutics and Pharmacokinetics, Faculty of Ph...

Tiotropium bromide monohydrate is an anticholinergic drug with specificity for muscarinic receptors, proposed to be used for the long-term, once-daily, maintenance treatment of bronchospasm and dyspnea associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. The proposed dosage of tiotropium is inhalation of the contents of one capsule (18 μg of ...

Gennaro Agrimi1,2*, Annamaria Russo1,2 and Maria Antonietta Ricci1,2 1Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Orabona 4, 70125 Bari, Italy 2CIRCC Interuniversity Consortium Chemical Reactivity and Catalysis, Via Celso Ulpiani 27, 70126 Bari, Italy *Corresponding author: Gennaro Agrimi, Assistant professor, Department of Biosciences, Biotechnologi...

Please find here attached the draft Clinical Pharmacology/Biopharmaceutics Review of NDA 22,527.

Professor Arto Urtti had his 60th birthday in December 2016. He is currently the Professor of Biopharmaceutics at the University of Helsinki and University of Eastern Finland (UEF). He was the editor-in-chief of European Journal of Pharmaceutical Sciences (EJPS) in 2001–2011, and this special issue of EJPS is dedicated to Arto in honour of his 60th birthday. The celebrations include a scientifi...