PURPOSE Population-based cohort study on the risk of anxiety and depression in patients with blepharitis is limited. This study evaluated whether blepharitis patients are at a higher risk of anxiety and depression. DESIGN A retrospective cohort study. METHODS We used the universal insurance claims data from 1997 to 2010 in Taiwan to identify annually patients with newly diagnosed blephariti...

PURPOSE The aims of our study were to compare the ocular microbial communities of humans with and without blepharitis in an attempt to elucidate which microorganisms may cause blepharitis. METHODS Bacterial 16S rRNA genes of eyelash and tear samples from seven blepharitis patients and four healthy controls were sequenced using a pyrosequencing method, and their bacterial community structures ...

PURPOSE OF REVIEW To summarize the key literature and our research experience regarding Demodex infestation as a potential cause of ocular inflammatory diseases with a special emphasis on Demodex blepharitis. RECENT FINDINGS Two distinct Demodex species have been confirmed as a cause of blepharitis: Demodex folliculorum can cause anterior blepharitis associated with disorders of eyelashes, an...

PATHoGEnEsis Anterior blepharitis is oft en associated with excessive bacterial growth on the lid margins. Th e microbes involved are typically the same species that normally reside there, including Staphylococcus epidermidis and Staphylococcus aureus.2 While questions remain about the role(s) of bacteria in blepharitis, it appears that toxic exoenzymes produced by the colonizing species—partic...

Blepharitis is characterized by chronic inflammation of the lid margins, which may appear as simple hyperemia or as a true inflammation. It may occur in two forms anterior and posterior. The eyelid margins can become inflamed, irritated, and itchy when these glands produce abnormal secretions. Blepharitis is often seen in patients with acne rosacea, a generalized illness of oil glands. Anterior...

Blepharitis, one of the most commonly treated ophthalmic conditions, can also be one of the most frustrating for the managing clinician. Although this is due in part to the chronic nature of the disease, the diversity of therapeutic options and lack of definitive scientific evidence for any single course of treatment also add significant challenge to clinical management. Despite these difficult...

Demodex folliculorum has been incriminated in the development of blepharitis although much controversy persist. Some authors suggest that Demodex is a direct pathogen in chronic palpebral conditions while others consider the saprophyte to be innocuous to skin. We conducted a prospective study of eyelashes in 48 patients with blepharitis (totally 96 eyes) and 48 healthy persons (totally 96 eyes)...

Blepharitis is a common inflammatory disease of the eyelid. Posterior blepharitis affects the posterior lamella of the eyelid and involves inflammation of the meibomian glands, whereas anterior blepharitis affects the anterior lamella of the eyelid and the eyelashes; either version can be inflammatory or infectious in nature. Each of these conditions can incite or propagate the other; anterior ...

A total of 50 patients suffering both from atopic skin disease and different clinical forms of blepharitis have been included in this study. Microbiological investigations (for bacteria and fungi) of the lid margins were performed in all cases. In 21 (42%) of the patients an ulcerative blepharitis which heavily involved the follicles of the lashes was diagnosed. The remaining 29 cases presented...