evidence acquisition electronic medical data bases (including pubmed and scopus) from first of january 1975 to 30th of july 2015 were searched. the key words used for the relevant articles search were catheter, venous, prevention, impregnated, bloodstream, chlorhexidine-silver sulfadiazine, rifampicin-minocycline, and rifampicin-miconazole. this review focuses on the evidence on the efficacy an...

background bloodstream infection (bsi) is an important cause of mortality and morbidity and among the most common health-care associated infections. in this study we described the frequency of occurrence and antimicrobial susceptibility patterns of nosocomial and community-acquired bsi isolates from a teaching hospital in tehran, iran. patients and methods this cross-sectional study was conduct...

Critically ill patients with acute renal failure (ARF) treated with renal replacement therapy (RRT) have a high mortality. The authors evaluated a cohort of 704 consecutive intensive care unit (ICU) patients with ARF treated with RRT to determine whether there was an increased incidence of nosocomial bloodstream infection and whether this resulted in a worse outcome. The incidence of nosocomial...

UNLABELLED Although some studies have examined the epidemiology of bloodstream infections after liver transplantation, they were based in single centers and did not identify bloodstream infections treated in other hospitals. METHODS We retrospectively examined a cohort of 7912 adult liver transplant recipients from 24 transplant centers using 2004 to 2012 International Classification of Disea...

OBJECTIVE To determine whether catheter-associated bloodstream infections were associated with increased lengths of stay in pediatric intensive care units and hospitals and increased healthcare costs in critically ill children. Previous studies have shown that hospital-acquired bloodstream infections are associated with longer stays in pediatric intensive care units, increased hospital costs, a...

background and objectives: coagulase negative staphylococcus (cons) is frequently isolated from blood cultures but their significance is difficult to interpret. cons bacteria which are often previously dismissed as culture contaminants are attracting greater importance as true pathogens in the past decades. clinical evaluation of these isolates suggests that although there is a relative increas...

OBJECTIVE To investigate the pathogenesis of bloodstream infection by Staphylococcus epidermidis, using the molecular epidemiology, in high-risk neonates. METHODS We conducted a prospective study of a cohort of neonates with bloodstream infection using central venous catheters for more than 24h. "National Healthcare Safety Network" surveillance was conducted. Genotyping was performed by DNA f...

BACKGROUND Bloodstream infections (BSI) are frequently seen after solid organ transplantation. The incidence of bloodstream infections differs among the types of transplantation. The microbiological features and antimicrobial resistance patterns change from centre to centre. AIMS To evaluate the incidence and spectrum of aetiological agents of bloodstream infections among solid organ transpla...

We performed a prospective study of bloodstream infection to determine factors independently associated with mortality. Between February 1999 and July 2000, 929 consecutive episodes of bloodstream infection at two tertiary care centers were studied. An ICD-9-based Charlson Index was used to adjust for underlying illness. Crude mortality was 24% (14% for community-onset versus 34% for nosocomial...