purpose: ‏to determine the visual and anatomic outcomes of epikeratoplasty in 7 eyes of 6 patients with keratoglobus. method: in a retrospective interventional case series, seven eyes of six patients with keratoglaobus (kgb) aged 5 to 39 years underwent epikeratoplasty. three patients (3 eyes) had blue sclera, hypermobile joints, and consanguineous parents and 3 patients (4 eyes) had only kgb. ...

We aimed to describe congenital keratoglobus with blue sclera in two siblings with overlapping Marshall/Stickler phenotype. Two sisters (ages four and six) with bilateral high astigmatism were evaluated by slit-lamp microscopy. Corneal topography and pachymetry maps were also obtained. Slit-lamp examination revealed that both corneas were globular in shape with peripheral corneal thinning. Pach...

An Indian case of Alport's syndrome who had association of keratoglobus and blue sclerae is described.

PURPOSE Iontophoresis has been used for drug delivery across the cornea for many years. We sought to test whether small charged dyes and DNA can be transferred across human sclera by an electric field. METHODS Full-thickness human scleral fragments were embedded vertically in an agarose gel and positioned to completely span individual gel lanes. The scleral fragments were located approximatel...

IntRoductIon Osteogenesis imperfecta (OI), also known as brittle bone disease or Lobstein syndrome, is characterized by blue or gray sclerae, variable short stature, dentinogenesis imperfecta, hearing loss, and recurrent fractures. Based on clinical, genetic, and radiological features, Sillence et al.[1] classified the OI into four subtypes including type I: Mild, common, with blue sclera; type...

Nevus of Ota is a rare congenital hamartoma the dermal melanocytes causing blue-grey hyperpigmentation eye and adnexa. The condition usually unilateral but rarely it can be bilateral. A 28-year-old lady from West Bengal, India, visited Ophthalmology outpatient department with complaints blackish discoloration left side face periorbital region. On examination, large (5x6 cm) lesion was noted on ...