introduction: glycoconjugates are a class of glycoproteins or glycolipids, their terminal sugars are responsible for cell-cell and/or cell-extracellular matrix interactions. aberrant glycosylation of these compounds are one of the most important aspects of cellular transformation, metastasis and escape of tumoral cells from immune system and resistance to antineoplastic drugs. recent studies sh...

BACKGROUND Metaplastic breast carcinoma is a rare aggressive malignant neoplasm. The purposes of this study are to review the pathologic features and clinical outcomes of metaplastic breast carcinoma compared to invasive ductal carcinoma and to evaluate the prognosis of metaplastic breast carcinoma. METHODS The cases of 55 patients with metaplastic breast carcinoma presenting between 1991 and...

Papillary carcinoma of the thyroid constitutes 80% of thyroid malignancies in adults. Females are affected at least twice as often as males. It metastasizes to distant sites very rarely, but to the cervical nodes quite often. Occasionally metastatic lymph node enlargement is the sole presenting feature. t.3.6.7 The tumor is slow growing and sometimes the patient has good survival even in s...

OBJECTIVE The study was aimed at investigating the clinical and biological features and survival outcomes of patients who were treated for metastatic inflammatory and noninflammatory breast carcinoma. SUBJECTS AND METHODS One hundred and sixty-seven metastatic breast cancer patients were enrolled into this study and divided into two groups: inflammatory (n = 46) and noninflammatory (n = 121)....

Most breast malignancies arise from epithelial elements and are categorized as carcinomas. IDC not otherwise specified (NOS) and ductal carcinoma in situ are common breast cancers and account for about 85% of breast cancers (1). Unusual breast malignancies may be broadly divided into ILC, well-differentiated subtypes of IDC, cancers of stromal origin, and metastatic neoplasms (2). Well-differen...

background: breast cancer is the malignancy in humans and other mammals. several risk factors are involved in their appearance such as higher hormone levels and obesity. identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...

Most breast carcinoma are hormone dependent. Two-thirds of breast cancers have estrogen or progesterone receptor positivity. Conflicting results regarding the clinical correlation between breast carcinoma and thyroid diseases have been reported. The objective of this study was to determine the thyroid profile in patients with newly diagnosed benign and malignant breast tumors. Serum samples wer...

background: the present study was performed to investigate the effects of trace elements particularity se, zn and cu on tumor genesis in breast cancer. methods: the inhibitory effect of se, zn and cu, on telomerase activity was analyzed in human breast tumor tissues and breast cancer (t47d) cells. tissue specimens from 24 women with benign breast disease and 32 women with breast cancer specimen...