The increasing global public health concern of antimicrobial resistance (AMR) necessitates exploration of natural antimicrobial agents as potential alternatives. This study aims to investigate antimicrobial activities of Saharan actinomycetes, with specific focus on the strain Streptomyces fimbriatus AC31, that holds promising potential as an alternative to combat AMR. In this context, 32 actin...

Two new antibiotics have been obtained from culture filtrates of an unidentified species of Streptomyces. These antibiotics are of special interest because of their high potency and their extreme toxicity. Because they are yellow in color and are produced by a Streptomyces, they have been named xanthomycin A and xanthomycin B. The organism, designated Streptomyces 94, is one of a series isolate...

Enterocin is a new antibiotic isolated from cultures of two strains of Streptomyces, which were given the names Streptomyces candidus var. enterostaticus WS-8096 and variant M-127 of Streptomyces viridochromogenes. Its elementary analysis and mass spectroscopic measurement suggest the molecular formula is C22H20010. The ultraviolet absorption gave two maximal peaks at 250 nm and 283 nm in metha...

During our continuous search for antibiotic producing actinomycetes, a variant of Streptomyces species was isolated from soils of Andhra Pradesh in India. The morphological, cultural, physiological and biochemical characters were studied, compared to known species and identified as a new variant of Streptomyces azureus and designated as streptomyces azureusvargossypii. The antibiotic activity o...

actinomycetes were isolated from marine sediment samples collected from the east coast of chennai, tamil nadu, india. well diffusion and agar plug methods were used for the evaluation of antibiotic production by these isolates against drug resistant methicillin- resistant staphylococcus aureus (mrsa) and vancomycin resistant enterococci (vre). the potential isolate vitbrk2 was mass cultured for...

Actinomycetes were isolated from marine sediment samples collected from the east coast of Chennai, Tamil Nadu, India. Well diffusion and agar plug methods were used for the evaluation of antibiotic production by these isolates against drug resistant Methicillin- resistant Staphylococcus aureus (MRSA) and vancomycin resistant Enterococci (VRE). The potential isolate VITBRK2 was mass cultured for...

conclusions the crude extract of streptomyces sp. acs52 had high antibacterial activity against a wide spectrum of bacteria and could be of interest due to its features such as ability to grow at low temperatures and alkaline ph levels. results streptomyces sp. acs52 is a cold-resistant alkalophilic bacterium strain with antibacterial activity against a broad spectrum of pathogenic bacteria. th...

Kalafungin is a new antimicrobial agent obtained from the culture broth of a soil isolate of Streptomyces tanashiensis, designated Streptomyces tanashiensis strain Kala UC-5063. Kalafungin is a chemically stable, nonpolyene agent which is ex-extremely inhibitory in vitro against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria, and, to a lesser extent, gram-negative bacte...

Lavendomycin, a new basic peptide antibiotic containing novel amino acids, has been isolated from the culture broth of a streptomyces designated as Streptomyces lavendulae subsp. brasilicus. The antibiotic obtained as colorless crystals (C29H50N10O8, MW 666) is active against Gram-positive bacteria in vitro and in vivo, however, inactive against Gram-negative bacteria and fungi. An acute toxici...

In the course of our search for new antibiotics produced by Streptomyces sp., a water-soluble antibiotic, effective against gram-negative bacteria, was obtained from the nitrate of a culture broth of Streptomyces No. 5879 isolated from a soil sample collected in Aizu area (Fukushima prefecture). Antibiotic No. 5879 appears to be a novel one from its physico-chemical and biological properties, a...