Calendula officinalis is an annual herb from Mediterranean origin which is popularly used in wound healing and as an anti-inflammatory agent. In this study, the ethanolic extract, the dichloromethane, and hexanic fractions of the flowers from plants growing in Brazil were produced. The angiogenic activity of the extract and fractions was evaluated through the chorioallantoic membrane and cutane...

Model studies of the influence lectin-containing extracts medicinal plants St. John's wort (Hypericum perforatum L.), common yarrow (Achillea millefolium marigold (Calendula officinalis L.) and dwarf evergreen (Helichrysum arenarium (L.) Moench.) on growth development wheat, oat, barley rye at beginning their ontogenesis. They testify to specificity action in relation model objects, which is pr...

In this study, 17 edible flowers (Allium ursinum L., Borago officinalis Calendula Centaurea cyanus Cichorium intybus Dianthus carthusianorum Lavandula angustifolia Mill., Leucanthemum vulgare (Vaill.) Lam., Paeonia Primula veris Robinia pseudoacacia Rosa canina pendulina Salvia pratensis Sambucus nigra Taraxacum officinale Weber, and Tropaeolum majus L.) were investigated to assess their sensor...

The role of the aldose reductase in type 2 diabetes is widely described. Therefore, it is of interest to identify plant derived compounds to inhibit its activity. We studied the protein-ligand interaction of 267 compounds from different parts of seven plants (Allium sativum, Coriandrum sativum, Dacus carota, Murrayyakoneigii, Eucalyptus, Calendula officinalis and Lycopersicon esculentum) with a...

three major flavonoid fractions were separated from a methanol extract of calendula officinalis flowers by preparative tlc. these fractions were evaluated for the inhibition of parent and tamoxifen resistant t47d human breast cancer cells. we also examined the effect of quercetin and isorhamnetin on the growth of parent and resistant t47d cells in the presence and absence of tamoxifen. it was f...

Prostaglandin E(2) (PGE(2)), the most relevant eicosanoid promoting inflammation and tumorigenesis, is formed by cyclooxygenases (COXs) and PGE(2) synthases from free arachidonic acid. Preparations of the leaves of Salvia officinalis are commonly used in folk medicine as an effective antiseptic and anti-inflammatory remedy and possess anticancer activity. Here, we demonstrate that a standard et...

The article is devoted to a review of the literature on problem overcoming negative outcomes genitourinary syndrome menopause (GSM). It known that woman in almost 30–40% her life, and according WHO, by 2030, 1.2 billion women will be postmenopause. At same time, there an increase life expectancy developed countries, which also leads number with GSM. presents pathogenetic mechanisms development ...