BACKGROUND Late effects (LEs) after cancer treatment are increasing. After childhood cancer, substantial risks include physical, psychological and social LE and vary with age. Teenagers and young adults (TYA) present with particular cancers; their risk of LE may relate to cancer site, treatment or their age itself. The LEs after TYA-onset cancers are described in relation to age at diagnosis of...

Reductions in risks to children's health comprise an important part of the benefits analysis for the Hazardous Waste Combustion (HWC) MACT standards. The risk analysis specifically targets children in estimating risks from HWC facility emissions. Additionally, recent initiatives of the EPA and other branches of the federal government have emphasized the necessity of addressing the subject of en...

BACKGROUND Indoor radon has been determined to be the second leading cause of lung cancer after tobacco smoking. There is an increasing need among radiation practitioners to have numerical values of lung cancer risks for men and women, ever-smokers and never-smokers exposed to radon in homes. This study evaluates individual risks for the Canadian population exposed to radon in homes at differen...

Public perception and anxiety of familial cancer have increased demands for clinical counseling, which may be well equipped for gene testing but less prepared for counseling of the large domain of familial cancer with unknown genetic background. The aim of the present study was to highlight the full scope of familial cancer and the variable levels of risk that need to be considered. Data on the...

INTRODUCTION Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. METHODS Occupation in a baking-related job was identified from the subjects' job histories. ORs adjusted for log(age), s...

PURPOSE To estimate the radiation-related lung cancer risks associated with annual low-dose computed tomographic (CT) lung screening in adult smokers and former smokers, and to establish a baseline risk that the potential benefits of such screening should exceed. MATERIALS AND METHODS The estimated lung radiation dose from low-dose CT lung examinations corresponds to a dose range for which th...

Since the atomic bombings of Hiroshima and Nagasaki in 1945, and the subsequent reports of raised cancer risks among survivors in the two cities, there has been interest and concern about risks arising from this and other nuclear incidents, such as the 1986 Chernobyl accident. This article reviews methodological aspects associated with the detection of cancer risks in groups exposed to ionising...

The CHEK2 1100delC protein-truncating mutation has a carrier frequency of f0.7% in Northern and Western European populations and confers an f2-fold increased risk of breast cancer. It has also been suggested to increase risks of colorectal and prostate cancer, but its involvement with these or other types of cancer has not been confirmed. The incidence of cancer other than breast cancer in 11,1...