To avoid the undesired effects of distance concentration in high-dimensional spaces, previous work has already advocated the use of fractional p norms instead of the ubiquitous Euclidean norm. Closely related to concentration is the emergence of hub and anti-hub objects. Hub objects have a small distance to an exceptionally large number of data points while anti-hubs lie far from all other data...

A p-hub center network design problem is definition of some nodes as hubs and allocation of non-hub nodes to them wherein the maximum travel times between any pair of nodes is minimized. The distinctive feature of this study is proposing a new mathematical formulation for modeling costs in a p-hub center problem. Here, instead of considering costs as a linear function of distance, for the first...

one main group of a transportation network is a discrete hub covering problem that seeks to minimize the total transportation cost. this paper presents a multi-product and multi-mode hub covering model, in which the transportation time depends on travelling mode between each pair of hubs. indeed, the nature of products is considered different and hub capacity constraint is also applied. due to ...

Ejaculated mammalian spermatozoa contain a complex yet specific population of mRNA. However, the possible roles that mRNA has in early zygotic and embryonic development remain unclear. We found that Dby mRNA is selectively retained in capacitated mouse spermatozoa, and is transferred into the oocyte during fertilization by reverse transcription-polymerase chain reaction even though no DBY prote...

The present was conducted to separate heparin binding proteins (HBP) of capacitated sperm extracts and determine their relationship with acrosome reaction and semen fertility of bulls (n=30). Fourteen immunoreactive bands in capacitated spermatozoa of bulls (135, 100, 75, 70, 65, 55, 48, 45, 33, 31, 26, 24, 20 and 18 kDa) were detected in western blots following incubation with anti-HBP antibod...

This paper studies a closed queueing network containing a hub (a state dependent queueing system with service depending on the number of units residing here) and k satellite stations, which are GI/M/1 queueing systems. The number of units in the system, N , is assumed to be large. After service completion in the hub, a unit visits a satellite station j, 1 ≤ j ≤ k, with probability pj , and, aft...

Design of network, through which data, packages or even people can be transported, is an important issue for achieving a desired level of service quality at an acceptable cost. For this purpose, it is possible to design a network comprised of nodes that are connected to each other with dedicated lines. However, this kind of solution will not be cost effective. In order to decrease the total tra...

Purpose: This paper aims to propose a new model called the stochastic green capacitated p-median problem with simulation-based optimisation approach. An integer linear programming mathematical is built considering total emission produced by vehicles and uncertain parameters including travel cost for vehicle from particular facility customer amount of CO2 emissions produced. We also develop algo...