BACKGROUND Selected patients with cardiac sarcoidosis undergo heart transplantation, but outcomes may be adversely affected by recurrent cardiac sarcoidosis or progressive extra-cardiac sarcoidosis. OBJECTIVES We present our single-center experience of patients with cardiac sarcoidosis who underwent heart transplantation. METHODS Consecutive patients that underwent heart transplantation bet...

Cardiac sarcoidosis is a rare complication of pulmonary sarcoidosis, causing granulomatous inflammation the myocardium, ultimately resulting in infiltrative cardiomyopathy. Through fibrotic inflammation, cardiac predisposes patients to multiple complications, such as conduction abnormalities, ventricular arrhythmias, heart failure, and sudden death. Due adverse prognosis abnormalities these pat...

objective: we sought to determine the usefulness of the 99mtc-mibi (mibi) washout rate for the evaluation of steroid therapy in cardiac sarcoidosis (cs). methods: eleven cs patients underwent mibi myocardial spect both before and 6 months after initiating steroid therapy. the washout rate (wor) of mibi was calculated using early and delayed polar map images. the washout score (wos) of mibi was ...

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology. We report an unusual case of sarcoidosis in a woman presenting with cardiac sarcoidosis and massive splenomegaly with a familial history of cardiac sarcoidosis. Cardiac sarcoidosis was diagnosed based on electrocardiogram, echocardiogram, 18F-fluoro-2-deoxyglucose positron emission tomography (18F-FDG-PET) and skin histol...

BACKGROUND Sarcoidosis is an inflammatory disorder of immune dysregulation characterized by non-caseating granulomas that can affect any organ. Cardiac sarcoidosis is an under-recognized entity that has a heterogeneous presentation and may occur independently or with any severity of systemic disease. Diagnosing cardiac sarcoidosis remains problematic with endomyocardial biopsies associated with...

Cardiac involvement in sarcoidosis is associated with poor prognosis. (18)F-FDG PET can detect the presence of cardiac sarcoidosis, assess disease activity, and serve as a means to monitor treatment response in patients with cardiac sarcoidosis.

Background Cardiac death is the leading cause of mortality in patients with sarcoidosis. However, the incidence of cardiac sarcoidosis in those with extracardiac disease has yet to be formally examined. Cardiovascular magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) may identify the myocardial infiltration of cardiac sarcoidosis (CS), and thus allow risk stratification of...

Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by noncaseating granulomas in involved organs. Organs involved with sarcoidosis include lymph nodes, skin, lung, central nervous system, and eye. Only 40-50% of patients with cardiac sarcoidosis diagnosed at autopsy have the diagnosis made during their lifetime. Cardiac sarcoidosis can manifest itself as comple...

Some patients with sarcoidosis can have cardiac involvement. Impairment of the cardiac sympathetic nerve activity is seen in about 50% of the sarcoidosis patients with small fiber neuropathy. In this case we present a sarcoidosis patient with small fiber neuropathy and cardiac symptoms with a cardiac sympathetic dysfunction, assessed with I-123 MIBG SPECT. After 5 months of treatment with carve...

BACKGROUND Clinically evidenced cardiac involvement in systemic sarcoidosis occurs in approximately 5% of patients, whereas post-mortem examinations identify cardiac sarcoidosis in over 60% of cases. OBJECTIVE Given the inconsistency of diagnostic approaches, we took aim at prospectively investigating the prevalence of cardiac sarcoidosis by cardiovascular magnetic resonance (CMR) in a primar...