background/purpose: although habitual consumption of xylitol reduces cariogenic streptococci levels, its effect on beneficial oral streptococci is less clear. the main aim of the study is to investigate the effect of short-term xylitol consumption on the oral beneficial streptococci level of saliva, streptococcus sanguinis and s. mitis . material and methods: twenty four volunteers with a media...

background: consistency, backing process and content differences could influence cariogenic potential of foods. the aim was to compare plaque ph changes following consumption of two types of bread with different physical characteristics. methods: in this clinical trial, interproximal plaque ph of 10 volunteers with high risk of dental caries (saliva streptococcus mutans > 10 5 , high dental car...

We use three-dimensional holographic particle tracking to perform microrheological measurements of model gelled media, including the polysaccharide pellicle of dental biofilms created by the common cariogenic oral pathogen Streptococcus mutans. Nanometerresolution video-rate holographic tracking of embedded colloidal spheres provides accurate measurements of the gels’ complex viscoelastic modul...

iron deficiency is the most common form of malnutrition in developing countries. iron containing supplements have been used effectively to solve this problem. in children, because of teeth staining after taking iron drops, parents have the idea that iron drops are the cause of tooth decay; therefore, they limit this vital supplement in their children's diet. hereby, we evaluate the histologic e...

Undecalcified mature enamel sections were used to observe the sequence of ultrastructural changes of enamel crystals and Streptococcus mutans biofilm in the early stages of caries. Human enamel blocks were incubated from 1 to 7 days with S. mutans suspension, and the pH of biofilm was measured. They were processed for light microscopic and transmission electron microscopy observations, and the ...

Objective: Presently, one of the most common oral diseases is dental caries, which a biofilm-mediated disease. Lawsone methyl ether (LME) has shown promising antibacterial activity due to its 1,4-napthoquinone structure. Recently, 1,2,3-triazole scaffold been used in structural modification potential antimicrobial agents. To develop novel anticaries agents, structure with N-substituted 1,2,3-tr...

Glycosyltransferase (Gtf) is one of the crucial virulence factors of Streptococcus mutans, a major etiological pathogen of dental caries. All the available evidence indicates that extracellular polysaccharide, particularly glucans produced by S. mutans Gtfs, contribute to the cariogenicity of dental biofilms. Therefore, inhibition of Gtf activity and the consequential polysaccharide synthesis m...

BACKGROUND Fixed orthodontic appliance (FOA) increases the cariogenic microorganisms of mouth including candida. The aim was to evaluate the pharmacodynamic effects of some antibacterial drugs in combination with most applicable antifungal agents on candida isolated from patients with FOA. METHODS Three antifungal agents (amphotericin B (AMB), ketoconazole (KET), and itraconazole (ITZ)) and t...

background: today, electronic mass media such as television (tv), influence behavioral patterns of their audiences. this study aimed to evaluate what messages on food advertisements related to oral health were transmitted (appeals) and how they were transferred (performance methods & artistic techniques) in islamic republic of iran broadcasting (irib). methods: in this cross sectional study, br...

The present study was designated to evaluate the antimicrobial activities of various solvent extracts from fruits of Terminalia chebula. The preliminary antimicrobial activities of the extracts against cariogenic organisms were tested by using disc diffusion assay. The methanolic extract showed higher antimicrobial activity against all the cariogenic organisms tested. Based on this finding, the...