how to cite this article: sanyal sh, duraisamy sh, garga chu. mri brain in evaluation of floppy children: a case series. iran j child neurol. autumn 2015; 9(4): 65-74. abstract objective hypotonia is a common clinical entity well recognized in pediatric age group, which demands experienced clinical assessment and an extensive array of investigations to establish the underlying disease process. ...

abstract hypotonia is a serious neurologic problem in neonatal period. although hypotonia is a nonspecific clinical finding but it is the most common motor disorder in the newborn. the objective of this study was to determine the frequency of neonatal hypotonia then to ascertain of the most common causes methods this cross –sectional prospective study was carried out on the 3281 term infants ho...

Objective: To determine the relative frequency of specific disorders that present with hypotonia in Iran. Methodology: It is a retrospective, cross–sectional study in which 107 children with hypotonia, aged one month to three years, were evaluated in Baqyiatallah Hospital between June 2003 and June 2006. Children were categorized into groups of central and peripheral hypotonia, and specific dia...

Identifying the underlying cause of congenital hypotonia remains difficult, despite advances in diagnostic laboratory and imaging techniques. Clinical evaluation strategies and standardized developmental tests can assist in differentiating hypotonia resulting from primary involvement of the upper motoneuron (central hypotonia) versus that involving the lower motoneuron and motor unit (periphera...

AIM Hypotonia is a symptom of diminished tone of skeletal muscle associated with decreased resistance of muscles to passive stretching, which can be caused by abnormalities of the central nervous system, any element of the lower motoneuron, or both. Hypotonia is not a specific diagnosis, but can be part of over 500 different genetic disorders, with many other conditions waiting to be identified...

Objective Hypotonia is a common clinical entity well recognized in pediatric age group, which demands experienced clinical assessment and an extensive array of investigations to establish the underlying disease process. Neuroimaging comes as great help in diagnosing the disease process in rare cases of central hypotonia due to structural malformations of brain and metabolic disorders and should...

Hypotonia is characterized by reduced resistance to passive range of motion in joints versus weakness, which is a reduction in the maximum muscle power that can be generated. (Dubowitz, 1985; Crawford, 1992; Martin, 2005) Based on strong research evidence, central hypotonia accounts for 60% to 80% of cases of hypotonia, whereas peripheral hypotonia is the cause in about 15% to 30% of cases. Dis...

Introduction: Electromyography (EMG) is an invaluable diagnostic tool to reach a diagnosis in patients with hypotonia. The objective of this study was observe the EMG patterns children presented as floppy baby. Methods: It cross-sectional conducted neurophysiology department National Institute Neurosciences and hospital over 4 years. Floppy children, aged 1 month 5 years, referred laboratory fo...

Floppy infants exhibit poor control of movement, delayed motor skills, and hypotonic motor movement patterns. Weak infants always have hypotonia, but hypotonia may exist without weakness. Some indications of CNS abnormality are because of poor state of alertness, lack of response to visual and auditory stimuli, inability to manage co-ordinated functions like swallowing and sucking noted that th...

Background: Hypotonia is a frequent neurological manifestation with numerous etiologies, but recognizing the cause challenge. First, it's necessary to differentiate hypotonia as peripheral, central or mixed. Signs of are normo/hyperreflexia, developmental delay, cognitive delay and/or epileptic seizures associated and normal creatine phosphokinase (CPK). After ruling out environmental risk fact...