BACKGROUND Chlorhexidine gluconate is a widely used antimicrobial agent. Adding chlorhexidine and quaternary ammonium compounds to filling materials, such as composite resins, acrylic resins, and glass ionomer cements increases the antibacterial property of restorative materials. This study includes antibacterial property of glass ionomer restorative cements with chlorhexidine gluconate. AIM ...

CONTEXT Nosocomial infections are an important cause of morbidity and mortality after cardiac surgery. Decolonization of endogenous potential pathogenic microorganisms is important in the prevention of nosocomial infections. OBJECTIVE To determine the efficacy of perioperative decontamination of the nasopharynx and oropharynx with 0.12% chlorhexidine gluconate for reduction of nosocomial infe...

BACKGROUND Oronine H(®) ointment, which contains chlorhexidine gluconate as its active component, is a well known disinfectant, and has been widely used for treatment of acne in Japan. In this study, we investigated the inhibitory effect of this ointment on the formation of comedones induced by application of 50% oleic acid on the orifices of the external auditory canals of rabbits. METHODS T...

BACKGROUND Chlorhexidine gluconate-impregnated dressings have become widely adopted as a means to reduce the risk for catheter-associated bloodstream infections. These dressings release antiseptic under occlusion onto the skin surrounding catheter insertion sites. Although chlorhexidine gluconate is a known cause of contact dermatitis, the phenotypic range of this adverse effect of chlorhexidin...

PURPOSE Bloodstream infections related to use of catheters, particularly central-line catheters, are an important cause of patient morbidity, mortality, and increased health care costs. This study evaluated the efficacy of skin disinfection with chlorhexidine gluconate compared with povidone-iodine solution in preventing catheter-related bloodstream infection. DATA SOURCES Multiple computeriz...

A wide variety of antimicrobial cationic agents, such as chlorhexidine gluconate, are commonly used in antiseptic preparations in the prevention of nosocomial infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In this study was investigated the activity of chlorhexidine gluconate against MRSA and methicillin-sensitive Staphylococcus aureus (MSSA). The quantitative suspensi...

INTRODUCTION Several studies have evaluated the efficacy of home use of chlorhexidine before surgery to reduce bacterial colonization. However, these studies have provided conflicting evidence about the potential efficacy of this strategy in decreasing bacterial loads and infection rates across surgical populations, and no prior study has analyzed the benefit of this intervention before spine s...

OBJECTIVE The objective of this study was to determine the cell surface hydrophobicity of 40 oral Candida albicans isolates obtained from smokers, diabetics, asthmatics using steroid inhalers, and healthy individuals, following brief exposure to subtherapeutic concentrations of chlorhexidine gluconate. MATERIALS AND METHODS Forty C. albicans oral isolates (10 isolates each from smokers, diabe...

AIM This study evaluated the antibacterial activity and dimensional stability of irreversible hydrocolloids mixed with different concentrations of chlorhexidine gluconate instead of water. MATERIALS AND METHODS Experimental specimens (45 specimens) were prepared and allocated into three groups of 15 each. Group I: Impression material mixed with distilled water served as control. Groups II and...

A storage test on chlorhexidine gluconate (0.004%) in aqueous or simulated contact lens solutions, conducted for 6 months in various containers, suggested [l] that loss of activity by a surface adsorption process was occurring. It has been reported [2] that contact lens solutions containing chlorhexidine gluconate (0.~5%) stored at room temperature in the dark for 6 months in polypropylene, pol...