نتایج جستجو برای: cholinergic antagonists

تعداد نتایج: 68579  

Journal: :avicenna journal of phytomedicine 0
mahnaz amini lung and tuberculosis research centre, mashhad university of medical sciences, mashhad, i. r. iran hamid khosrojerdi department of toxicology, imam reza hospital, mashhad university of medical sciences, mashhad, i. r. iran reza afshari department of toxicology, imam reza hospital, mashhad university of medical sciences, mashhad, i. r. iran

objectives: datura stramonium (ds) is a common weed along roadsides, in cornfields and pastures and in waste areas. it belongs to the family solanaceae and its toxic components are tropane belladonna alkaloids. it has been used voluntarily by teenagers for its hallucinogenic effect. the plant is named in iran as tatoore. symptoms and signs of acute d. stramonium poisoning usually are similar to...

Journal: :journal of emergency practice and trauma 0
mahesh chand meena forensic medicine and toxicology, lady hardinge medical college, new delhi-110001, india kuldeep panchal forensic medicine and toxicology, lady hardinge medical college, new delhi-110001, india mukta rani forensic medicine and toxicology, lady hardinge medical college, new delhi-110001, india

abstract oculocardiac reflex (ocr) sometimes occurs as a result of pressure on the eye or traction of the intraorbital surrounding structures during ophthalmic surgery. this can result in bradycardiac arrhythmia and cardiac arrest. a 45-year-old female was undergoing an elective squint correction surgery of one eye under local anaesthesia in a private hospital in december 2013. the patient was ...

Mehrnoush Moghaddasi Shahrbanoo Oryan, Zeynab Sarlak,

Objective(s):  The cholinergic system plays an important role in learning and memory. This study investigated the effects of curcumin (turmeric extract) and the cholinergic system and their interaction on memory retention of passive avoidance learning in adult male Wistar rats. Materials and Methods: At first, an injection cannula was implanted in right ventricles of the animals. One week afte...

Journal: :Vision Research 1996
Bernhard Jurklies Alain Kaelin-Lang Günter Niemeyer

To identify cholinergically mediated components in the optic nerve response (ONR) we studied effects of cholinergic agonists and antagonists in the arterially perfused cat eye. Acetylcholine, carbachol, scopolamine, quinuclidinylbenzilate and mecamylamine were applied intra-arterially in micromolar concentrations. Recordings of rod- and cone-driven ERG accompanied those of the ONR and revealed:...

Journal: :iranian journal of basic medical sciences 0
zeynab sarlak department of biology, science and research branch, islamic azad university, tehran, iran shahrbanoo oryan department of biology, science and research branch, islamic azad university, tehran, iran mehrnoush moghaddasi razi herbal medicines research center, lorestan university of medical sciences, khoramabad, iran

objective(s):  the cholinergic system plays an important role in learning and memory. this study investigated the effects of curcumin (turmeric extract) and the cholinergic system and their interaction on memory retention of passive avoidance learning in adult male wistar rats. materials and methods: at first, an injection cannula was implanted in right ventricles of the animals. one week after...

2014
Larry M. Jordan J. R. McVagh B. R. Noga A. M. Cabaj H. Majczyński Urszula Sławińska J. Provencher H. Leblond Serge Rossignol

Previous experiments implicate cholinergic brainstem and spinal systems in the control of locomotion. Our results demonstrate that the endogenous cholinergic propriospinal system, acting via M2 and M3 muscarinic receptors, is capable of consistently producing well-coordinated locomotor activity in the in vitro neonatal preparation, placing it in a position to contribute to normal locomotion and...

Journal: :Revista Neurociências 2023

Introduction. There is evidence that neurotransmitters and their systems may be involved in the pathophysiology of motor stereotypies Autism Spectrum Disorder. Objective. Conduct a review to assess on correlations between stereotyped behaviors changes neurotransmitter systems, by analyzing original articles an animal model. Method. Studies published January 2000 2021 were searched six databases...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2008
Matthew A Sullivan Huanmian Chen Hitoshi Morikawa

The striatum plays a central role in sensorimotor learning and action selection. Tonically active cholinergic interneurons in the striatum give rise to dense axonal arborizations and significantly shape striatal output. However, it is not clear how the activity of these neurons is regulated within the striatal microcircuitry. In this study, using rat brain slices, we find that stimulation of in...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Pavel Pakhotin Enrico Bracci

How the extent and time course of presynaptic inhibition depend on the action potentials of the neuron controlling the terminals is unknown. We investigated this issue in the striatum using paired recordings from cholinergic interneurons and projection neurons. Glutamatergic EPSCs were evoked in projection neurons and cholinergic interneurons by stimulation of afferent fibers in the cortex and ...

Marjan Pazouki, Mohammad Reza Zarrindast, Shadi Nassiri-Rad,

  In this study, we investigated the effect of nicotinic receptor agonists and antagonists on the analgesic response to morphine in the formalin test. In experiments conducted in mice, nicotine produced an early dose-dependent analgesic effect. At a dose of 0.5 mg/kg, mecamylamine, a nicotinic receptor inhibitor, suppressed the analgesic effect induced by 0.1 mg/kg nicotine in both stages of th...

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