نتایج جستجو برای: chronic lymphocytic leukemia
تعداد نتایج: 733768 فیلتر نتایج به سال:
chronic lymphocytic leukemia (cll) and chronic myeloid leukemia (cml) are the most common leukemias of the elderly (>43 year). however, the sequential occurrence of cml followed by cll in the same patient is extremely rare. in our report, a 52-year-old female was diagnosed with cll (type of bone marrow (bm) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months ...
it has recently been shown that ror1, a member of the receptor tyrosine kinase family, is overexpressed in leukemic b cells of chronic lymphocytic leukemia (cll) and a subset of acute lymphoblastic leukemia (all). in this comparative study the expression profile of ror1 mrna was investigated in iranian patients with cll and acute myelogenous leukemia (aml) and the results were compared with tho...
1. dept. of hematology and medical oncology, kermanshah university of medical sciences, kermanshah, iran 2. students research committee, kermanshah university of medical sciences, kermanshah, iran 3. medical biology research center, kermanshah university of medical sciences, kermanshah, iran corresponding author: masoud sadeghi, msc. tel: (+98) 9185960644 ema...
background b-cell chronic lymphocytic leukemia (b-cll) is the most common form of leukemia in adults. some reports showed that expression of zap70 gene and chromosomal abnormality are two prognostic factors in management of b-cll objectives in this study, we determined zap70 mrna expression level in the del17p13, del6q21 and del11q13 subgroups of iranian b-cll patients to investigate prognostic...
Genome-editing systems such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology have uncovered new opportunities to model diseases chronic lymphocytic leukemia. CRISPR/Cas9 is an important means of advancing functional studies Chronic Lymphocytic Leukemia (CLL) through the incorporation, elimination and modification somatic mutations in CLL models.
conclusions it was demonstrated that the presence of del6q21 in b-cll patients indicates poor prognosis and on the contrary, presence of del17p13 points at the good prognostic value of the disease. results deletion of 17p13 was found in 11 (16.6%) and deletion 6q21 was present in 5 (7.5%). statistical analyses were performed to investigate the correlation of these molecular-cytogenetic findings...
Introduction: Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in adults living in Western countries. with a diverse clinical course that due to life expectancy less than two years between patients finding ,new therapeutic strategies is essential for it. Curcumin as the biologic active of turmeric, has many biological properties such as anti-inflammatory, anti-oxidant, anti-diab...
Idelalisib is a novel treatment option for patients with chronic lymphocytic leukemia. A rare, but, fatal complication of using Idelalsib drug induced pneumonitis. This article presents case pneumonitis in patient leukemia along brief discussion management plan.
Background: B-cell chronic lymphocytic leukemia is the most frequent leukemia in the western world while T-cell large granular lymphocytic leukemia with cytotoxic (CD8+/CD3+CD4-) immunophenotype is rare. There is much ongoing interest regarding the interaction between T cells and B-cell chronic lymphocytic leukemia cells. Methods: Peripheral blood and bone marrow samples from a 72 year-old-man ...
The importance of the tumor microenvironment in chronic lymphocytic leukemia is widely accepted. Nevertheless, the understanding of the complex interplay between the various types of bystander cells and chronic lymphocytic leukemia cells is incomplete. Numerous studies have indicated that bystander cells provide chronic lymphocytic leukemia-supportive functions, but it has also become clear tha...
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