introduction conservation and management of landscapes and beautiful sceneries is one of the necessities of establishing and maintaining the protected areas. analysis of landscape visual quality has an important place in landscape planning and designing. in this way, reviewing effective criteria and discovering the simple patterns which affect the landscapes is the most important step of modeli...

in today’s world the concept of “city” without effective landscape is out of imagination. being focal points for human life and activities, cities have to consider the structure and functions which are influenced by natural systems. in this regard, landscapes are inevitable parts of cities with an essential metabolic role. unlike most countries which don’t have to deal with water shortage as a ...

During allosteric motions proteins navigate rugged energy landscapes. Hence, mapping of these multidimensional landscapes into lower dimensional manifolds is important for gaining deeper insights into allosteric dynamics. Using a recently developed computational technique, we calculated the free energy difference between the open and closed states of adenylate kinase, an allosteric protein whic...

Alpine grazing reduces blazing’ is a widely and strongly held view concerning the effects of livestock grazing on fuels, and therefore fire behaviour and impact, in Australia’s high country landscapes. As a test of this hypothesis, we examined the patterns of burning across the alpine (treeless) landscapes of the Bogong High Plains in Victoria, following the extensive fires of January 2003. Dat...

We generalize the degree-organizational view of real-world networks with broad degree distributions in a landscape analog with mountains (high-degree nodes) and valleys (low-degree nodes). For example, correlated degrees between adjacent nodes correspond to smooth landscapes (social networks), hierarchical networks to one-mountain landscapes (the Internet), and degree-disassortative networks wi...

The 'new view' of proteins sees protein reactions as parallel processes occurring along funnelled energy landscapes. These landscapes are generally not smooth, but are superimposed by hills and valleys of different heights and widths leading to roughness on the energy surface. In the present paper, we describe the origins of protein energy landscape roughness, measurements of its scale and its ...

The notion of fitness landscapes, a map between genotype and fitness, was proposed more than 80 years ago. For most of this time data was only available for a few alleles, and thus we had only a restricted view of the whole fitness landscape. Recently, advances in genetics and molecular biology allow a more detailed view of them. Here we review experimental and theoretical studies of fitness la...

The NMDA receptor family of glutamate receptor ion channels is formed by obligate heteromeric assemblies of GluN1, GluN2, and GluN3 subunits. GluN1 and GluN3 bind glycine, whereas GluN2 binds glutamate. Crystal structures of the GluN1 and GluN3A ligand-binding domains (LBDs) in their apo states unexpectedly reveal open- and closed-cleft conformations, respectively, with water molecules filling ...

The phenomena of selection and coexistence are modelled as chemical pattern formation by competition for a given Ž . resource in heterogeneous spatial fields fitness landscapes . The reactions form a closed reproductive cycle so that total concentration of species and their building-blocks is kept constant in time. Eigen’s ‘constant overall organization’ conditions can be view as a particular c...