Subjective cognitive impairment may be a very early at-risk period of the continuum of dementia. However, it is difficult to discriminate at-risk states from normal aging. Thus, detection of the early pathological changes in the subjective cognitive impairment period is needed. To elucidate these changes, we employed diffusion tensor imaging and volumetry analysis, and compared subjective cogni...

primary sjorgen syndrome is one of the commonest autoimmune diseases with characteristic of involvement of lachrymal and salivary glands, but other organ involvements as peripheral and central nervous system are also possible. the reported case is a 23 year old lady presented with progressive sensory ataxia and weakness of four limbs, bilateral sensory hearing loss and cognitive impairment with...

The conversion rate of cognitive impairment to Alzheimer's disease is 1 to 25% per year. Early detection of cognitive impairment will thus become a major concern, particularly when pharmacological intervention for preventing or delaying conversion will prove effective. If simple carotid artery intima media thickness (IMT) measurements were to predict cognitive impairment, IMT could become one o...

OBJECTIVE the incidence of cognitive impairment is increasing; however, little is known about the prevalence and risk factors for cognitive impairment of elderly people in China. This report focuses on investigating the relationship between cigarette smoking, alcohol drinking and cognitive impairment in elderly people. METHODS 3012 participants aged 60 years old and over were enrolled from si...