background previous studies showed that shallomin, the active antimicrobial constituent of persian shallot, has a wide range of antibacterial and antifungal properties. objectives the objective of this randomized clinical trial was to evaluate the effectiveness of topical shallomin alcoholic solution in treatment of cold sore. patients and methods a total of 60 volunteers who met the inclusion ...

BACKGROUND Herpes simplex virus type 1 (HSV-1) infects >70% of the United States population. We identified a 3-megabase region on human chromosome 21 containing 6 candidate genes associated with herpes simplex labialis (HSL, "cold sores"). METHODS We conducted single nucleotide polymorphism (SNP) scans of the chromosome 21 region to define which of 6 possible candidate genes were associated w...

Herpes simplex (or just “Herpes”) is another name for the “cold sore” virus. It commonly causes local blisters and scabbing around the mouth and nose but occasionally infects the eye where, unlike the skin, it may cause scarring or chronic inflammation. The cold sore virus is a different strain of herpes than the one associated with sexually transmitted disease; ocular herpes is not an STD. Col...

Herpes simplex virus is a widespread disease affecting about one-third of the world’s population. Many individuals suffer from its painful and debilitating manifestations, which greatly impact daily living and can lower one’s self-esteem and confidence. It is therefore vital to understand this disease process including its acquisition, replication, transmission, clinical manifestations, diagnos...

The outcome of any interaction between a virus and host is determined by genetic and environmental factors and is manifest as either susceptibility to or chronicity of infection or severity of disease [1]. This interplay between host genetics and viral strain genomic sequence has been well defined in murine models of different viral infections, such as murine cytomegalovirus, retroviruses (Frie...

A randomized prospective double-blind study was performed to compare the efficacy of a single 5 min 1072 nm narrow waveband light application against topical aciclovir applied five times daily in the treatment of herpes labialis. Treatment was initiated within 36 h of the onset of symptoms and the end point was defined as the day that the crust was discarded leaving an uninterrupted underlying ...

conclusions according to our results, by omitting probable risk factors of incidence of sore throat and evaluation of role of hormonal changes in women represented in menstrual cycles, there was no significant association between menstrual cycle and sore throat incidence. results of 100 patients, in the first six hours, 51 patients had sore throat and 49 had no pain. during the first 6 hours, 3...

The common cold is an acute, self-limiting, viral inflammation of the mucosa of the upper respiratory tract. It causes nasal discharge and congestion, sneezing, a sore throat and a cough. The common cold actually describes an array of similar conditions caused by a vast number of different viruses. It is most often caused by infection with rhinoviruses (50-80%) and coronaviruses [1] . It may al...