Collagens are a primary component of the extracellular matrix and functional ligands for inhibitory immune receptor leukocyte-associated immunoglobulin-like (LAIR)-1. LAIR-2 is secreted protein that can act as decoy by binding collagen with higher affinity than LAIR-1. We propose collagens promote evasion interacting LAIR-1 expressed on cells, releases LAIR-1-mediated suppression. Analysis publ...

conclusions the results suggest the important role of the antioxidant system potentiation in the prevention of myocardial damage. results cell degenerative changes, pyknotic nuclei, contraction bands, edema, and loosening of collagen in between muscle fibers were observed during ischemia-reperfusion. myocardial architecture and cellular morphology were recovered in co-administration groups, esp...

Collagen is a ubiquitous protein present in the extracellular matrix of all major metazoan animals, with approximately 28 different human collagen types described literature, each unique physicochemical properties. Collagens found broad application cosmeceutical, pharmaceutical, and biomedical fields can be isolated from environmentally sustainable sources such as marine byproducts, which are a...

The biosynthesis, structural diversity, and functionality of collagens of sponge origin are still paradigms and causes of scientific controversy. This review has the ambitious goal of providing thorough and comprehensive coverage of poriferan collagens as a multifaceted topic with intriguing hypotheses and numerous challenging open questions. The structural diversity, chemistry, and biochemistr...

Marine biodiversity is expressed through the huge variety of vertebrate and invertebrate species inhabiting intertidal to deep-sea environments. The extraordinary “forms functions” exhibited by marine animals suggests they are a promising source bioactive molecules provides potential inspiration for different biomimetic approaches. This diversity familiar biologists has led intensive investigat...