نتایج جستجو برای: conditioned medium

تعداد نتایج: 259755  

Journal: :Laboratory investigation; a journal of technical methods and pathology 1995
C J Meininger S E Brightman K A Kelly B R Zetter

BACKGROUND Capillary hemangiomas, the most common tumors in young children, consist of proliferating capillary vessels and endothelial cells. These tumors also contain large numbers of mast cells, compared with the normal surrounding skin or tissue. We have recently shown that stem cell factor (SCF), the gene product of the murine steel locus, can act as a chemoattractant for mast cells. In thi...

Journal: :PLoS ONE 2008
Héctor Alejandro Guidobaldi María Eugenia Teves Diego Rafael Uñates Agustín Anastasía Laura Cecilia Giojalas

Sperm chemotaxis in mammals have been identified towards several female sources as follicular fluid (FF), oviduct fluid, and conditioned medium from the cumulus oophorus (CU) and the oocyte (O). Though several substances were confirmed as sperm chemoattractant, Progesterone (P) seems to be the best chemoattractant candidate, because: 1) spermatozoa express a cell surface P receptor, 2) capacita...

2015
Xinyang Hu Ling Zhang Jing Jin Wei Zhu Yinchuan Xu Yan Wu Yingchao Wang Han Chen Keith A. Webster Huiqiang Chen Hong Yu Jian’an Wang

Heparanase plays important roles in tumor angiogenesis. Our previous study demonstrated that hypoxic preconditioning (HPC) enhanced the angiogenic and therapeutic effects of mesenchymal stem cells (MSCs), effects that were paralleled by enhanced heparanase expression. This study was designed to elucidate the role of heparanase in the improved therapeutic properties of HPC-MSCs and to explore un...

Journal: :Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991
B Korczak R S Kerbel J W Dennis

Acquisition of metastatic competence by tumor cells is frequently accompanied by increased expression of extracellular proteases capable of degrading basement membrane and extracellular matrix. However, very little is known about how the genes encoding these enzymes and their inhibitor proteins are regulated in metastatic versus nonmetastatic cells. In this report, we have compared autocrine an...

Journal: :Molecular cancer research : MCR 2009
Philip M Carpenter Anh V Dao Zahida S Arain Michelle K Chang Hoa P Nguyen Shehla Arain Jessica Wang-Rodriguez Soon-Young Kwon Sharon P Wilczynski

Host interactions with tumor cells contribute to tumor progression by several means. This study was done to determine whether mammary epithelium could interact with breast carcinoma by producing substances capable of inducing motility in the cancer cells. Conditioned medium of immortalized 184A1 mammary epithelium collected in serum-free conditions induced dose-dependent motility in the MCF-7 b...

2015
Pornthep Sirimahachaiyakul Ravi F. Sood Lara A. Muffley Max Seaton Cheng-Ta Lin Liang Qiao Jeffrey S. Armaly Anne M. Hocking Nicole S. Gibran Suzie Chen

INTRODUCTION Abnormal pigmentation following cutaneous injury causes significant patient distress and represents a barrier to recovery. Wound depth and patient characteristics influence scar pigmentation. However, we know little about the pathophysiology leading to hyperpigmentation in healed shallow wounds and hypopigmentation in deep dermal wound scars. We sought to determine whether dermal f...

1999
Jing S. Hu Dale B. Gelman Robert A. Bell Dwight E. Lynn

Effects of conditioned media prepared from cell lines derived from 11 insect species (six families, three orders) on the in vitro growth and development of the egg parasitoid Edovum puttleri were investigated. The parasitoid exhibited significantly different responses to the various insect cell line-conditioned media that were incorporated into the artificial diets. When cell lines were derived...

2014
Eudes Euler de Souza Lucena Fausto Pierdoná Guzen José Rodolfo Lopes de Paiva Cavalcanti Maria Jocileide de Medeiros Marinho Wogelsanger Oliveira Pereira Carlos Augusto Galvão Barboza Miriam Stela Mariz de Oliveira Costa Expedito Silva do Nascimento Júnior Jeferson Sousa Cavalcante

A number of evidences show the influence of the growth of injured nerve fibers in peripheral nervous system as well as potential implant stem cells (SCs). The SCs implementation in the clinical field is promising and the understanding of proliferation and differentiation is essential. This study aimed to evaluate the plasticity of mesenchymal SCs from bone marrow of mice in the presence of cult...

Journal: :Journal of immunology 1983
E T Dayton B Perussia G Trinchieri

Human promyelocytic cells lines treated with conditioned medium from PHA-stimulated leukocytes acquire several phenotypic and functional markers of differentiated monocytes. In this paper, we demonstrate that promyelocytic cells treated with conditioned medium express, among other markers, monocyte-specific and HLA-DR antigens absent from the parental cells and become potent effectors of antibo...

Journal: :The Journal of Cell Biology 1990
R Quarto B Dozin C Tacchetti G Campanile C Malfatto R Cancedda

Single cells from enzymatically dissociated chick embryo tibiae have been cloned and expanded in fresh or conditioned culture media. A cloning efficiency of approximately 13% was obtained using medium conditioned by dedifferentiated chondrocytes. A cloning efficiency of only 1.4% was obtained when conditioned medium from hypertrophic chondrocytes was used, and efficiencies of essentially 0 were...

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