نتایج جستجو برای: conditioned medium

تعداد نتایج: 259755  

عزیزیان, سارا, مدرسی فر, خشایار, مروج, حمیده, میر معصومی, معصومه, نیک نژاد, حسن,

Background and Objective: It has recently been shown that the application of amniotic membrane conditioned medium is effective in cancer treatment. In this study, the effect of amniotic stem cells conditioned medium on the activity of Hsp90 and Cdk4 expression, were investigated in cancer cells. Materials and Methods: Two cancer cell lines HeLa and MDA-MB-231 were treated with the supernatan...

ژورنال: طب جنوب 2023
Haji Ghasem Kashani , Maryam, Omidvar , Forozan, Tabatabai , Tayebeh Sadat,

Background: The effect of conditioned medium on apoptosis and invasion of MCF-7 is still debated. Carnosic acid, a component of rosemary extract, is also reported to have anti-cancer property. Therefore, we studied the occurrence of apoptosis through AIF-dependent pathway in MCF-7 cells treated with conditioned medium and rosemary extract by evaluating the expression of AIF, P53, Bcl-2 and Bax ...

حیدری , محمود, اسماعیل نژادمقدم, امیر, انتظاری نجف آبادی, مائده, قاسمی حمیدآبادی, هاتف, کریمپور ملکشاه, عباسعلی,

Background and purpose: The purpose of this study was to evaluate the effect of mouse embryonic fibroblast cells conditioned medium on resumption of meiosis, in vitro maturation of immature mouse oocytes, fertilization and derived embryos development. Material and Methods: Immature oocytes denuded at the germinal vesicle (GV) stage were obtained from female NMRI mice 46-48 hrs after injecti...

Journal: :iranian biomedical journal 0
نوروز دلیرژ nowruz delirezh لیلا ماجدی leila majedi سیامک عصری رضایی siamak asri rezaei هادی رنجکش زاده hadi ranjkeshzadeh

background: dendritic cells (dc) induce tumor or pathogen-specific t cell responses in humans. several laboratories have developed culture systems, including maturation factors for human dc from peripheral blood monocytes. we comprehensively compared standard maturation stimulus, an autologous monocyte-conditioned medium (mcm), with heparin for their ability to promote uniformly mature dc that ...

Journal: :مجله دانشگاه علوم پزشکی شهرکرد 0
اکرم منصوری بیدکانی akram mansouri-bidekani biology dept, faculty of basic sciences, shahrekord university, shahrekord, i.r. iran, tel:شهرکرد، دانشگاه شهرکرد، دانشکده علوم پایه، گروه زیست شناسی، تلفن: 09387388036، فریبا اسماعیلی fariba esmaeili biology dept., shahrekord university, shahrekord, i.r. iranگروه زیست شناسی، دانشگاه شهرکرد، شهرکرد، ایران فریبا هوشمند fariba houshmand medical plants research center, shahrekord university of medical sciences, shahrekord, i.r. iran.مرکز تحقیقات گیاهان داروئی، دانشگاه علوم پزشکی شهرکرد، شهرکرد، ایران. زهره حاجی شریفی zohre hajisharifi biology dept., shahrekord university, shahrekord, i.r. iranگروه زیست شناسی، دانشگاه شهرکرد، شهرکرد، ایران

background and aims: understanding β-cell function at the molecular level will likely facilitate the development of β-cells manufacture techniques. the aim of the present study was to investigate the pancreatic and duodenal homeobox 1 (pdx-1) gene expression into dtz-stained cellular clusters originating from emberyonal carcinoma cells. methods: this implemental -fundamental study was accomplis...

Journal: :modares journal of medical sciences: pathobiology 2012
forouzan yousefi masoumeh ebtekar masoud soleimani seyed mahmoud hashemi

objective: this study investigated the effects of adipose-derived mesenchymal stem cells (mscs) and conditioned medium injection on cell infiltration in the brains of an experimental c57bl/6 mice model of autoimmune encephalomyelitis (eae). methods: eae was induced with myelin oligodendrocyte glycoprotein (35-55 peptides) in 20 mice. mscs were obtained from the adipose tissue of c57bl/6 mice a...

اسدی, معصومه, دلیرژ, نوروز, غلامی, کیکاوس, فرخی, فرح, نجاتی, وحید, گنجی‌بخش, میثم,

Background: Nowadays, dendritic cells (DC) are used for tumor immunotherapy as they can induce immune responses against tumor cells. In this research, we comprehensively studied the maturation stimulus addition, PHA-activated T-cell (PHA- TCM) conditioned medium, autologous monocyte-conditioned medium (MCM) and TNF-α for their ability to promote uniformly mature dendritic cells that eli...

ژورنال: طب جنوب 2022
Haji Ghasem Kashani , Maryam, Hojati , Vida, Kousha , Abotaleb, Vaezi , Gholam Hossein,

Background: Adipose tissue stem cells (ASCs) cause faster repair of damaged tissue posttransplantation by releasing growth factors in neurodegenerative diseases. ASCs secrete factors in the culture medium called conditioned medium (CM) in vitro. This study investigated the expression of neurotrophin genes in vitro culture and transplant of ASCs in Parkinsonian rats. Materials and Methods: In th...

ژورنال: پژوهش در پزشکی 2014
بیات, محمد, خیرجو, راضیه, رجبی بذل, معصومه, محسنی فر, ژاله, پیریایی, عباس, گنجی, رسول,

Abstract Background: Diabetes is a metabolic chronic disorder that makes it difficult to heal wounds because of its complications. To this point, many studies on the use of mesenchymal stem cells in wound healing process particularly diabetic ulcers have been done. In this study, we evaluate the impact of mesenchymal stem cells-derived conditioned medium (MSC-CM) on diabetic wound strength. Mat...

Journal: :Journal of Visualized Experiments 2015

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