complication of infection with maternal varicella before 20 weeks of pregnancy. Prospective studies in Europe and North America have shown that the incidence of congenital varicella syndrome in maternal varicella contracted in the first 20 weeks of pregnancy is about 1%–2%. Based on this estimated risk (1%), on an estimated risk of varicella infection during pregnancy of two maternal infections...

Congenital varicella syndrome refers to the spectrum of fetal anomalies associated with maternal varicella zoster virus (VZV) infection during the first trimester of pregnancy. The syndrome is rare and the risk to the fetus uncertain. We describe an unusual case of congenital varicella syndrome in which hydrocephalus was the main consequence and likely represented VZV reactivation in utero.

congenital varicella syndrome encompasses a broad spectrum of malformations present in children of mothers who developed chickenpox during the fi rst 20 weeks of gestation. we report a case of a monochorionic diamniotic twin pregnancy, with maternal exposure to chickenpox during the thirteenth week of gestation, which produced one symptomatic and one healthy child.

Varicella (chickenpox) in pregnancy is unusual because most women of childbearing age are immune. It can, however, cause significant morbidity for the pregnant woman and in rare cases cause congenital varicella syndrome. The incidence of congenital varicella syndrome after maternal varicella during the first two trimesters is <1% across multiple cohort studies. Maternal infection in the third t...

In 1947, LaForet and Lynch first described the association between maternal infection by Varicellazoster virus during the beginning of gestation and congenital anomalies in the newborn(1). Today varicella during pregnancy is a very rare condition. Primary infection by varicella during gestation is estimated to affect one to seven per 10 thousand pregnant women(2). The Varicella-zoster virus is ...

Fetal varicella syndrome is a rare condition of the newborn, presenting with cutaneous scars, limb defects, ocular and central nervous system abnormalities. It is due to varicella or zoster developing in the fetus following maternal varicella infection during early pregnancy. We are reporting a case of congenital varicella syndrome following maternal varicella during the 17th week of pregnancy....

BACKGROUND The Pregnancy Registry for Varivax (Merck) was established to monitor for congenital varicella syndrome or other birth defects in the offspring of women who were exposed to varicella vaccine while pregnant. METHODS The registry receives voluntary reports from health care providers or consumers about women given the vaccine 3 months before or during pregnancy. Follow-up is conducted...

Background Varicella (chickenpox) is a common childhood disease, but if it develops during pregnancy, can have serious and undesirable consequences, including congenital varicella syndrome, maternal VZV pneumonia, neonatal infection; this lead to feto-maternal morbidity mortality. Antiviral therapy appropriate supportive care improve outcomes. This case report provides an overview of varicella-...

Vaccines that contain live attenuated varicella-zoster virus (VZV) (Varivax, ProQuad, and Zostavax [all products of Merck & Co., Inc.]) are contraindicated during pregnancy. To monitor the pregnancy outcomes of women inadvertently vaccinated with VZV-containing vaccines immediately before or during pregnancy, Merck and CDC established the Merck/CDC Pregnancy Registry for VZV-Containing Vaccines...