objective midazolam is a significant and effective drug for control of a life-threatening condition, generalized and partial refractory convulsive status epilepticus. the goal of this study was evaluation of midazolam efficacy for management of this serious disease and its two side effects, hypotension and respiratory failure. materials & methods our study was done using a quasi experimental me...

objective refractory convulsive status epilepticus (se) which does not respond to first line drugs (benzodiazepines, phenytoin and phenobarbital) heralds an emergency condition in pediatric neurology which can cause irreparable brain damage. there is no consensus on the choice of drug treatment for refractory generalized  convulsive status epilepticus in children. lidocaine is a valuable forgot...

non-convulsive status epilepticus (ncse) may present with several manifestations, many of which may not be obvious. the most important tool for the diagnosis of ncse is the electroencephalograph (eeg) pattern. this is a case report of a boy 9 years of age presenting with severe and continuous headache. he had received chemotherapy for histiocytosis, diagnosed at the age of 3.5 years. no evidenc...

The risk of long-term mortality and its predictors following convulsive status epilepticus in childhood are uncertain. We report mortality within 8 years after an episode of convulsive status epilepticus, and investigate its predictors from a paediatric, prospective, population-based study from north London, UK. In the current study, we followed-up a cohort previously ascertained during a surve...

PURPOSE To identify predictors of poor clinical outcome in patients presenting to the intensive care units with status epilepticus (SE), in particular for patients presenting with de novo status epileptics. METHODS A retrospective review was performed on patients admitted to the intensive care units with status epilepticus in two hospitals in Hong Kong over an 11-year period from 2003 to 2013...

Status epilepticus (SE) is the most frequent neurological emergency requiring admission on the intensive care unit (ICU). The classification of status epilepticus may be dichotomised into the “convulsive” and the “non-convulsive” form. Whereas the diagnosis of generalised convulsive status epilepticus (GCSE) is easily made in view of the evident manifestation, the diagnosis of nonconvulsive sta...

OBJECTIVE the purpose of this article is to describe the clinical and electroencephalographic features of four elderly patients diagnosed as having non-convulsive status epilepticus. METHODS four females ranging in age from 74 to 81 years were admitted to our hospital because of confusion and altered mental state. We recognised four distinctive entities: i) Absence status in a patient with pr...

Non-convulsive status epilepticus is an insidious condition and a challenging diagnosis for neurologists on call. The condition must, however, be recognized, since it constitutes a neurological emergency. Non-convulsive status epilepticus may also be associated as an additional complication with an acute neurologic disease, in which case an EEG recording is usually required. In addition, non-co...

CONTEXT The optimal pharmacologic treatment for early convulsive status epilepticus is unclear. OBJECTIVE To analyze efficacy, tolerability and safety data for anticonvulsant treatment of children and adults with convulsive status epilepticus and use this analysis to develop an evidence-based treatment algorithm. DATA SOURCES Structured literature review using MEDLINE, Embase, Current Conte...

INTRODUCTION Non-convulsive status epilepticus is a form of epileptic seizure that occurs without convulsions. Recent reviews suggest that the diagnosis of non-convulsive status epilepticus remains difficult. Here, we report the case of a patient with thyroid-stimulating hormone elevation misdiagnosed as subclinical hypothyroidism following non-convulsive status epilepticus. CASE PRESENTATION...