نتایج جستجو برای: crtc

تعداد نتایج: 63  

2016
Minkyung Kim Hoyeon Lee Jin-Hoe Hur Joonho Choe Chunghun Lim

Light is one of the strongest environmental time cues for entraining endogenous circadian rhythms. Emerging evidence indicates that CREB-regulated transcription co-activator 1 (CRTC1) is a key player in this pathway, stimulating light-induced Period1 (Per1) transcription in mammalian clocks. Here, we demonstrate a light-independent role of Drosophila CRTC in sustaining circadian behaviors. Geno...

2016
Yukinori Hirano Kunio Ihara Tomoko Masuda Takuya Yamamoto Ikuko Iwata Aya Takahashi Hiroko Awata Naosuke Nakamura Mai Takakura Yusuke Suzuki Junjiro Horiuchi Hiroyuki Okuno Minoru Saitoe

Accumulating evidence suggests that transcriptional regulation is required for maintenance of long-term memories (LTMs). Here we characterize global transcriptional and epigenetic changes that occur during LTM storage in the Drosophila mushroom bodies (MBs), structures important for memory. Although LTM formation requires the CREB transcription factor and its coactivator, CBP, subsequent early ...

Journal: :Cell 2015
Kristopher Burkewitz Ianessa Morantte Heather J.M. Weir Robin Yeo Yue Zhang Frank K. Huynh Olga R. Ilkayeva Matthew D. Hirschey Ana R. Grant William B. Mair

Low energy states delay aging in multiple species, yet mechanisms coordinating energetics and longevity across tissues remain poorly defined. The conserved energy sensor AMP-activated protein kinase (AMPK) and its corresponding phosphatase calcineurin modulate longevity via the CREB regulated transcriptional coactivator (CRTC)-1 in C. elegans. We show that CRTC-1 specifically uncouples AMPK/cal...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Run Shen Biao Wang Maria G Giribaldi Janelle Ayres John B Thomas Marc Montminy

The starvation-inducible coactivator cAMP response element binding protein (CREB)-cAMP-regulated transcription coactivator (Crtc) has been shown to promote starvation resistance in Drosophila by up-regulating CREB target gene expression in neurons, although the underlying mechanism is unclear. We found that Crtc and its binding partner CREB enhance energy homeostasis by stimulating the expressi...

2003
Yves Bertrand Marie-Lise Flottes L. Balado Joan Figueras Anton Biasizzo Franc Novak Stefano Di Carlo Paolo Prinetto Nicoleta Pricopi Hans-Joachim Wunderlich Jean-Pierre Van der Heyden

The paper deals with a European experience of education in industrial test of ICs and SoCs using remote testing facilities. The project addresses the problem of the shortage in microelectronics engineers aware with the new challenge of testing mixed-signal SoCs for multimedia/telecom market. It aims at providing test training facilities at a European scale in both initial and continuing educati...

2013
Yukinori Hirano Minoru Saitoe

Animals form and store memory, which advantageously adjusts their behavior later on. Although the growing body of evidences suggests the basic mechanisms of memory, it is not clear whether and in which physiological state memory functions can be altered. Here we discuss our recent study that mild fasting facilitates long-term memory (LTM) formation in Drosophila.(1) Canonical LTM in flies is in...

Journal: :Relations industrielles 1979

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Qianyi Luo Kristin Viste Janny Concha Urday-Zaa Ganesan Senthil Kumar Wen-Wei Tsai Afsaneh Talai Kelly E Mayo Marc Montminy Ishwar Radhakrishnan

Basic leucine zipper (bZip) transcription factors regulate cellular gene expression in response to a variety of extracellular signals and nutrient cues. Although the bZip domain is widely known to play significant roles in DNA binding and dimerization, recent studies point to an additional role for this motif in the recruitment of the transcriptional apparatus. For example, the cAMP response el...

Journal: :Education for Information 2022

This special issue launches from the challenges of white supremacy within Library and Information Studies (LIS) demonizing Critical Race Theory (CRT) American British societies. To address these through a commitment to practice as well theory, editorial team for this publication was formed tackle head on how racialised knowledge justice issues can also manifest in scholarly publishing spheres. ...

Journal: :Canadian Journal of Communication 1982

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید