the absence of cerebrospinal fluid (csf) pleocytosis in invasive meningococcal disease (imd) has been associated with an increased risk of death. it is unknown whether patients who lack a cellular response to central nervous system (cns) infection are at the same risk of adverse outcome as patiens without cns infection. to determine the frequency of presentation and outcome of three groups of c...

OBJECTIVES This study aims to describe the clinical characteristics of enteroviral meningitis in association with the absence of cerebrospinal fluid (CSF) pleocytosis. DESIGN This was a retrospective analysis of databases of patients diagnosed with enteroviral meningitis by CSF reverse transcription-PCR testing. Presence of CSF non-pleocytosis at each age group was analysed by use of the two ...

PURPOSE To determine the rate of cerebrospinal fluid (CSF) pleocytosis among children presenting with status epilepticus (SE) without proven central nervous system infection. METHOD We performed a retrospective cross-sectional study of all patients aged one month to 21 years of age who were evaluated in a single pediatric emergency department (ED) for SE between 1995 and 2012. We limited our ...

OBJECTIVES To determine the prevalence of and to identify risk factors for sterile cerebrospinal fluid (CSF) pleocytosis in a large sample of febrile young infants with urinary tract infections (UTIs) and to describe the clinical courses of those patients. DESIGN Secondary analysis of a multicenter retrospective review. SETTING Emergency departments of 20 North American hospitals. Patients ...

Background. Viral meningitis and encephalitis is typically characterized by a cerebrospinal fluid (CSF) lymphocytic pleocytosis. A CSF neutrophilic pleocytosis presentation has been described but its prognostic and clinical significance is unknown. The objectives of our study were to compare the clinical and laboratory characteristics of viral central nervous system (CNS) infections with CSF ne...

Background: Tuberculous meningitis (TBM) remains a serious health threat for children in developing countries. This study was aimed to analyze findings and duration of cyto-biochemical changes in CSF in children with TBM. Patients and Method: Over a period of 8 years (1989-1996) we have analyzed cyto-biochemical changes in CSF in 202 children with TBM. In 126 cases (62,4%) was have analyzed dur...

INTRODUCTION We hypothesized that pleocytosis, which is a marker of central nervous system (CNS) inflammation, would result in viral genetic equilibration or de-compartmentalization between HIV populations in the blood and cerebrospinal fluid (CSF), suggesting viral trafficking. METHODS Study subjects, who started or interrupted their antiretroviral treatment, had viral loads measured and clo...

BACKGROUND Cerebrospinal fluid (CSF) pleocytosis may be seen in asymptomatic HIV-infected individuals. This finding complicates interpretation of CSF abnormalities when such individuals are evaluated for other central nervous system infections. The goal of this study was to determine the relationship between CSF pleocytosis, central nervous system (CNS) antiretroviral penetration, adherence to ...

In a follow-up study of 24 patients with Guillain-Barré syndrome, 55% developed a cerebrospinal fluid (CSF) mononuclear pleocytosis, which persisted for 4 months or more. Raised index values of CSF-immunoglobulin G (IgG), CSF-IgA, and CSF-IgM, indicating synthesis of the immunoglobulin in question in the central nervous system, were found in 63, 35, and 25%, respectively. Agarose gel eletrophor...