Curcumin (Cum) has been reported to have potential chemo-preventive and chemotherapeutic activity through influencing various processes, inducing cell cycle arrest, differentiation and apoptosis in a series of cancers. However, the poor solubility of Cum limits its further applications in the treatment of cancer. We have previously reported Cum-loaded nanoparticles (Cum-NPs) prepared with amphi...

Curcumin (Cum), the principal polyphenolic curcuminoid, obtained from the turmeric rhizome Curcuma longa, is recently reported to have potential antitumor effects in vitro and in vivo. Docetaxel (Doc) is considered as first-line chemotherapy for the treatment of non-small cell lung cancer. Here we report for the first time that Cum could synergistically enhance the in vitro and in vivo antitumo...

PURPOSE Liver cancer, one of the most common cancers in China, is reported to feature relatively high morbidity and mortality. Curcumin (Cum) is considered as a drug possessing anti-angiogenic, anti-inflammation and anti-oxidation effect. Previous research has demonstrated antitumor effects in a series of cancers. MATERIALS AND METHODS In this study the in vitro cytotoxicity of Cum was measur...

Temozolomide (TMZ), a DNA alkylating agent, represents the most important chemotherapeutic option for the treatment of glioblastoma in the clinic. Despite its frequent use, the therapeutic efficacy of TMZ remains very limited due to its frequent resistance in glioblastoma. Previous evidence suggested that curcumin (CUM), an ingredient of the Indian spice turmeric, is able to sensitize glioblast...

This study examined the adoption prospects and challenges of rice-cum-fish production technology among rice and fish farmers in selected States in southern Nigeria (Delta, Edo, Lagos and Ondo States). Using questionnaire, data was sought from 720 sampled rice and fish farmers in the selected States. The data were analysed using descriptive statistics, logit regression. Results showed that more ...

Organic peroxides, widely used in the chemical and pharmaceutical industries, can act as skin tumor promoters and cause epidermal hyperplasia. They are also known to trigger free radical generation. The present study evaluated the effect of cumene hydroperoxide (Cum-OOH) on the induction of activator protein-1 (AP-1), which is linked to the expression of genes regulating cell proliferation, gro...

Vivamus, mea Lesbia, atque amemus, rumoresque senum severiorum omnes unius aestimemus assis. Soles occidere et redire possunt; nobis, cum semel occidit brevis lux, nox est perpetua una dormienda. Da mi basia mille, deinde centum, dein mille altera, dein secunda centum, deinde usque altera mille, deinde centum, dein, cum milia multa fecerimus, conturbabimus illa, ne sciamus, aut nequis malus inv...

The study examines the impact of the rice-cum-fish culture and the rice-mono culture on the rural households at Muktaghachha upazila of Mymensingh district in Bangladesh. Data were collected from 100 farmers of five villages following stratified random sampling technique. Activity budgets were prepared and comparisons were made through the tabular and statistical analyses. Both the rice-cum-fis...