Cinnamomum verum, also called true cinnamon tree, is employed to make the seasoning cinnamon. Furthermore, the plant has been used as a traditional Chinese herbal medication. We explored the anticancer effect of cuminaldehyde, an ingredient of the cortex of the plant, as well as the molecular biomarkers associated with carcinogenesis in human colorectal adenocarcinoma COLO 205 cells. The result...

objective: alpha-synuclein is a major component of protein plaques in synucleinopathies, particularly parkinson’s disease. the purpose of this study is to assess the inhibitory effects of cuminaldehyde on the fibrillation of alpha-synuclein. methods: alpha-synuclein was expressed in escherichia coli and subsequently purified. for the process of fibrillation, purified protein was incubated at 3...

malaria as one of the most recurrent infectious diseases caused by parasites of the genus plasmodium, kills several hundred thousand people especially in the tropical and subtropical regions of the world annually. terpenoids have served as the lead compounds to develop new antimalarial agents. the aromatic monoterpenoid, cuminaldehyde, isolated from the fruits of buniumpersicum was evaluated fo...

Here, we investigated the interaction of cuminaldehyde with a model carrier protein, bovine serum albumin (BSA). The formation BSA–cuminaldehyde complex was confirmed through ultraviolet–visible (UV–Vis) spectroscopy and further proven by detailed intrinsic fluorescence spectroscopic measurements. As observed, quenched tryptophanyl BSA. data, before analyses, were corrected for inner filter eff...

Phytopathogenic fungi can lead to significant cereal yield losses, also producing mycotoxins dangerous for human and animal health. The fungal control based on the use of synthetic fungicides can be complemented by "green" methods for crop protection, based on the use of natural products. In this frame, the antifungal activities of bergamot and lemon essential oils and of five natural compounds...

Seeds of cumin (Cuminum cyminum L.) are widely used as a spice for their distinctive aroma. C. have been in traditional medicine to treat variety diseases. Literature presents ample evidence biomedical activities which is attributed its bioactive secondary metabolites - terpenes, phenols, and flavonoids. Besides, health effects seeds experimentally validated through phytochemical analysis depic...

the essential oil from the seeds of cuminum cyminum l. was isolated by hydrodistillation method and the chemical composition was determined by gas chromatography-mass spectrometry (gc/ms). the yield of the oil was found to be 3.0% (on dry weight basis). a total of twenty six components, representing 96.7% of the oil were identified. cuminaldehyde (49.4%), p-cymene (17.4%), b-pinene (6.3%), a-ter...