Environmental pollution from pesticides is an important issue that attracts wide spread public concern. Among these organophosphate pesticides are routinely used in agriculture. Chloropyrifos toxicity has been largely associated with irreversible inhibition of acetyl-cholinesterase resulting in accumulation of acetylcholine in the cholinergic receptors. Organochlorine insecticides, caused degen...

Hepatoprotective Properties of Cuminum cyminum Seeds Powder as Post-Treatment for Acetaminophen-Induced Injury

introduction: estimating ephedrine’s effect on animal’s locomotor activity and evaluation of cumin fruit essential oil (feo) effect and mechanism of ephedrine-induced hyper-locomotion. methods: a new protocol developed for evaluation of manic behavior induced by ephedrine in a dose and time dependent manner. following the suppressive effects of cumin feo on acquisition and expression of ephedri...

Objective: To evaluate antihyperlipidaemic activity of methanolic extract of seeds of Cuminum cyminum L. in hyperlipidaemia in rabbits. Methods: This study was conducted in Pharmacology Department of University of Karachi; the duration of study was 30 days. Healthy rabbits were taken and hyperlipidaemia was induced by giving high cholesterol diet for four weeks. All animals were divided into th...

The antimicrobial activities of the ethyl acetate, acetone and methanol extract of 12 plant species were studied. The extract of Capsicum annuum (red pepper) (fruit) Zingiber officinale (ginger) (root), Cuminum cyminum (cumin), Alpinia ficinarum (galingale), Coriandrum sativum (coriander), Cinnamomun zeylanicum Nees (cinnamomun), Origanum onites L. (thyme), Folium sennae (senna), Eugenia caryop...

Various studies have indicated that peptic ulcers occurring during the course of diabetic state are more severe and often associated with complications such as gastrointestinal bleeding. This study is the first attempt to understand the pathogenesis of gastric ulcers occurring during the diabetic state considering alternate biochemical pathways using suitable markers and its amelioration by Cum...

Bacillus safensis strain VK was isolated from the rhizosphere of a cumin plant growing in the saline desert of Radhanpar, Gujarat, India. Here, we provide the 3.68-Mb draft genome sequence of B. safensis VK, which might provide information about the salt tolerance and genes encoding enzymes for the strain's plant growth-promoting potential.

Background: Cuminum cyminum fruit essential oil (FEO) dose-dependently can attenuate the expression of morphine tolerance and dependence in morphine-dependent mice. Objective: In this study, the effects of Cuminum cyminum FEO on acquisition and expression of morphine-induced conditioned place preference (CPP) in morphine-sensitized mice were studied. Methods: Repeated subcutaneous (s.c.) adm...

background: cuminum cyminum fruit essential oil (feo) dose-dependently can attenuate the expression of morphine tolerance and dependence in morphine-dependent mice. objective: in this study, the effects of cuminum cyminum feo on acquisition and expression of morphine-induced conditioned place preference (cpp) in morphine-sensitized mice were studied. methods: repeated subcutaneous (s.c.) admini...

Background: Cuminum cyminum (Cumin) and Curcuma longa (Turmeric) are plant derived spices which are commonly used as a part of everyday recipes in variety of cuisines. They are known causes of platelet dysfunction but Thrombotic thrombocytopenic purpura (TTP) following their consumption has never been reported in the literature. Primary cardiac involvement in TTP is a rare but fatal complicatio...