Abstract Cell structure modification techniques have the potential to improve curcuminoid recovery in Curcuma longa . In this study, different pre-treatments such as high hydrostatic pressure (HPP, processing), ultrasound (US), pulsed electric field (PEF), and ohmic heating (OH) were used on dried C. before aqueous extraction at pH 2.0, 5.0, 8.0. The released curcuminoids, cell disintegration i...

In the course of studies on the antioxidant mechanism of curcumin, its radical reaction was investigated. Curcumin was reacted with radical species, which were generated from the pyrolysis of 2, 2'-azobis(isobutyronitrile) under an oxygen atmosphere, and the reaction products from curcumin were followed by HPLC. The reaction at 70 degrees C gave several products, three of which were structurall...

Curcuminoids are a group of compounds with a similar chemical backbone structure but containing different numbers of methoxy groups that have therapeutic potential due to their anti-inflammatory and anti-oxidant properties. They mainly bind to albumin in plasma. These findings influence their body disposition and biological activities. Spectroscopic analysis using site specific probes on human ...

Curcumin, the active molecule present in Curcuma longa is known for its antitumour, antioxidant, antiarthritic, anti-amyloid, anti-ischemic, anti-inflammatory activities. In addition, it may also be effective in treating malaria, prevention of cervical cancer, etc. High-performance thin-layer chromatography (HPTLC) method has been employed for determination of curcumin in four varieties of turm...

Eight difluoroboron complexes of curcumin derivatives carrying alkyne groups containing substituents have been synthesized following an optimised reaction pathway. The complexes were received in yields up to 98% and high purities. Their properties as fluorescent dyes have been investigated. Furthermore, a strategy for the hydrolysis of the BF2 group has been established using aqueous methanol a...

A simple, sensitive, precise and specific method for the determination of curcuminoids and curcuminoid-loaded liposome formulation was developed using reverse-phase high-performance liquid chromatography method. The analysis was performed isocratically on Zorbax Eclipse XDB-C18 column (150×4 mm, 5 μm), analytical column using UV detector and mobile phase consisting of 0.1% orthophosphoric acid ...

Hydrogenated curcuminoids are the major metabolites of the curcumin and 'CuroWhite' is a unique blend of hydrogenated curcuminoids encapsulated with β-cyclodextrin. There is no particular scientific evidence for the toxicology regarding the hydrogenated curcuminoids, so the present work reports the results of the studies investigating the acute (single dose) and subchronic (repeatedly 90 days) ...