نتایج جستجو برای: d8
تعداد نتایج: 1255 فیلتر نتایج به سال:
Vaccinia virus (VACV) envelope protein D8 is one of three glycosaminoglycan adhesion molecules and binds to the linear polysaccharide chondroitin sulfate (CS). D8 is also a target for neutralizing antibody responses that are elicited by the smallpox vaccine, which has enabled the first eradication of a human viral pathogen and is a useful model for studying antibody responses. However, to date,...
We construct four kinds of 1/4 BPS solutions in massive IIA supergravity corresponding to D8-D0-F1, D8-D2, D8-D4 and D8-D6-NS5 systems. They include many known solutions as special cases. D8-D2 and D8-D4 solutions are represented by harmonic functions as usual, while the other two by solutions of non-linear differential equations. Because these four solutions can be argued in almost identical w...
PURPOSE To identify the types of malformations resulting from the administration of retinoic acid (RA) to Swiss mice on different days of pregnancy. METHODS Twenty-four pregnant Swiss mice were divided into 4 groups of 6 animals each. The experimental groups received a single intraperitoneal injection of RA (70 mg/kg) on gestational days 7, 8 and 9 (D7, D8 and D9), while control animals (C) r...
OBJECTIVE It has been hypothesized that monoclonal antibody D8/17 identifies a B lymphocyte antigen with expanded expression in patients with rheumatic fever, childhood onset obsessive-compulsive disorder (OCD), Tourette syndrome (TS) or prepubertal anorexia nervosa (AN). Our purpose was to replicate these studies in a Spanish population and to determine whether D8/17 identifies a subgroup of t...
We study four kinds of 1/4 BPS solutions in massive IIA supergravity corresponding to D8-D0-F1, D8-D2, D8-D4 and D8-D6-NS5 systems. We show that these solutions are reproduced without making nontrivial assumptions by using supersymmetry conditions. D8D2 and D8-D4 solutions are represented by harmonic functions, as usual, while the other two are represented by solutions of non-linear differentia...
INTRODUCTION We assessed the relationship between the plasma concentration of gefitinib and its efficacy in Japanese patients with advanced non-small cell lung cancer (NSCLC). METHODS Plasma trough levels of gefitinib were measured on days 3 (D3) and 8 (D8) by high-performance liquid chromatography in 44 patients with advanced NSCLC treated with 250 mg gefitinib daily. Eligibility criteria in...
The IMV envelope protein D8 is an adhesion molecule and a major immunodominant antigen of vaccinia virus (VACV). Here we identified the optimal D8 ligand to be chondroitin sulfate E (CS-E). CS-E is characterized by a disaccharide moiety with two sulfated hydroxyl groups at positions 4' and 6' of GalNAc. To study the role of antibodies in preventing D8 adhesion to CS-E, we have used a panel of m...
The German infectious disease surveillance system revealed an increase of epidemic keratoconjunctivitis (EKC) from an average of 320 cases/year (2001 to 2010) up to 2146 and 1986 cases in 2012 and 2013, respectively. From November 2011 until December 2013 (epidemic period) 85% of typed isolates were human adenovirus type 8 (HAdV-D8), whereas only low level circulation (19%) of HAdV-D8 was obser...
بررسی رفتار رودخانه ها نیازمند تجزیه و تحلیل مدلهای هیدرولوژیکی می باشد، این مدلها شامل استخراج شبکه آبراهه ای و بدست آوردن اطلاعات مربوط به آن مانند طول و شیب آبراهه می باشد، این بحث در پروژه های سدسازی و آبی بسیار حائز اهمیت است. با توجه به مسیر آبراهه ها، می توان بهترین مکان را برای احداث سد تعیین کرد. در این مطالعه حوزه رودخانه کارون به عنوان منطقه مورد مطالعه انتخاب شده است. با استفاده از ...
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