Article history: Received 29 March 2013 Available online 10 February 2014 JEL classification: C72 D83 D85

PEP mutase catalyzes the conversion of phosphoenolpyruvate (PEP) to phosphonopyruvate in biosynthetic pathways leading to phosphonate secondary metabolites. A recent X-ray structure [Huang, K., Li, Z., Jia, Y., Dunaway-Mariano, D., and Herzberg, O. (1999) Structure (in press)] of the Mytilus edulis enzyme complexed with the Mg(II) cofactor and oxalate inhibitor reveals an alpha/beta-barrel back...

Three Neuro-Fuzzy Inference Systems (ANFIS) including Grid Partitioning (GP), Subtractive Clustering (SCM) and Fuzzy C-means clustering Methods (FCM) have been used to predict the groutability of granular soil samples with cement-based grouts. Laboratory data from related available in litterature was used for the tests. Several parameters were taken into account in the proposed models: water:ce...

Active proton transfer through membrane proteins is accomplished by shifts in the acidity of internal amino acids, prosthetic groups, and water molecules. The recently introduced step-scan attenuated total reflection Fourier-transform infrared (ATR/FT-IR) spectroscopy was employed to determine transient pKa changes of single amino acid side chains of the proton pump bacteriorhodopsin. The high ...

Bacteriorhodopsin, a light activated protein that creates a proton gradient in halobacteria, has long served as a simple model of proton pumps. Within bacteriorhodopsin, several key sites undergo protonation changes during the photocycle, moving protons from the higher pH cytoplasm to the lower pH extracellular side. The mechanism underlying the long-range proton translocation between the centr...

We examine a simple economic model of network formation where agents benefit from indirect relationships. We show that small-world features—short path lengths between nodes together with highly clustered link structures—necessarily emerge for a wide set of parameters. (JEL: D85, A14, C72)

For the connections model of strategic network formation, with two-way flow of information and without information decay, specific parameter configurations are given for which Nash networks do not exist. Moreover, existence and the scope of Nash network architectures are briefly discussed. JEL Classification: C72, D85

A 2.0T gasoline engine was modified to a dual-injection engine. Numerical simulation method is used study the influence of fuel type and injection strategy on in-cylinder mixture formation process, combustion process soot emission The results show that an appropriate increase in intake port ratio can improve uniformity air-fuel mixture. Increasing system, proportion directly injected into cylin...