OBJECTIVE This study estimated the health impact, cost and cost-effectiveness of an integrated prevention campaign (IPC) focused on diarrhoea, malaria and HIV in 70 countries ranked by per capita disability-adjusted life-year (DALY) burden for the three diseases. METHODS We constructed a deterministic cost-effectiveness model portraying an IPC combining counselling and testing, cotrimoxazole ...

A quantitative microbial risk assessment (QMRA) was performed at four managed aquifer recharge (MAR) sites (Australia, South Africa, Belgium, Mexico) where reclaimed wastewater and stormwater is recycled via aquifers for drinking water supplies, using the same risk-based approach that is used for public water supplies. For each of the sites, the aquifer treatment barrier was assessed for its lo...

Background: This study uses data of the global burden of diseases (GBD) study 2010 to report death, disability-adjusted life year (DALYs), years of life lived with disability (YLDs) and years of life lost due to premature mortality (YLLs), attributed to suboptimal breastfeeding by age and gender during 1990 to 2010 in Iran. Materials and Methods:The GBD assessments were used, together with esti...

Background: To our knowledge, no systematic update on the descriptive epidemiology of endometriosis and its trends has been published based Global Burden Disease (GBD) datasets. investigate burden in 204 countries territories from 1990 to 2019. Methods: Data were extracted 2019 Estimated annual percentage changes (EAPCs) calculated assess incidence disability-adjusted life-years (DALYs) endomet...

OBJECTIVE Traumatic brain injury (TBI) is a major cause of death and disability, leading to great personal suffering and huge costs to society. Integrated knowledge on epidemiology, economic consequences and disease burden of TBI is scarce but essential for optimizing healthcare policy and preventing TBI. This study aimed to estimate incidence, cost-of-illness and disability-adjusted life years...

BACKGROUND Exposure to second-hand smoke is common in many countries but the magnitude of the problem worldwide is poorly described. We aimed to estimate the worldwide exposure to second-hand smoke and its burden of disease in children and adult non-smokers in 2004. METHODS The burden of disease from second-hand smoke was estimated as deaths and disability-adjusted life-years (DALYs) for chil...

BACKGROUND Obstetric hemorrhage is the leading cause of maternal mortality, particularly in low resource settings where delays in obtaining definitive care contribute to high rates of death. The non-pneumatic anti-shock garment (NASG) first-aid device has been demonstrated to be highly cost-effective when applied at the referral hospital (RH) level. In this analysis we evaluate the incremental ...