Double Data Rate Dynamic Random Access Memory (DDR DRAM) has become important to develop a low-power high performance DCC(Duty Cycle Corrector) with better duty cycle accuracy. DDR DRAM increases the speed using Successive Approximation Register Duty Cycle Corrector (SAR DCC). The proposed DCC circuit will be implemented in a 0.18um CMOS process. Here, Adjuster circuit delay line is being modif...

AIM To investigate the role of DCC gene inactivation in the development and progression of gastric cancer. METHODS Loss of heterozygosity and loss of expression of the DCC gene was studied in 51 surgical specimens of gastric cancer using detection based on polymerase chain reaction. RESULTS Loss of heterozygosity was found in 35.3% (18 of 51) of specimens and was detected more often in stag...

To achieve X-chromosome dosage compensation, organisms must distinguish X chromosomes from autosomes. We identified multiple, cis-acting regions that recruit the Caenorhabditis elegans dosage compensation complex (DCC) through a search for regions of X that bind the complex when detached from X. The DCC normally assembles along the entire X chromosome, but not all detached regions recruit the c...

Paranodal axoglial junctions are essential for the segregation of myelinated axonsinto distinct domains and efficient conduction of action potentials. Here, we show thatnetrin-1 and deleted in colorectal cancer (DCC) are enriched at the paranode in CNSmyelin. We then address whether netrin-1 signaling influences paranodal adhesionbetween oligodendrocytes and axons. In the absenc...

Netrin-1 modulates axonal growth direction and speed. Its best characterized receptor, Deleted in Colorectal Cancer (DCC), is localized to growth cones, but also observed in the cell bodies. We hypothesized that cell bodies sense Netrin-1 and contribute to axon growth rate modulation, mediated by the second messenger system. We cultured mouse cortical neurons in microfluidic devices to isolate ...

The aim of this study was to evaluate the sealing ability of materials filled in the orifice after root canal treatment. A total of 100 root canal-treated teeth were divided into six experimental groups: 1, Protect Liner F (PL); 2, Panavia F (PF); 3, DC core-Light cured (DCL); 4, DC core-Chemically cured (DCC); 5, Super-EBA (SE); 6, Ketac (KC). The materials were filled--to a depth of 4 mm--in ...

RNA-binding proteins (RBPs) control multiple aspects of post-transcriptional gene regulation and function during various biological processes in the nervous system. To further reveal the functional significance of RBPs during neural development, we carried out an in vivo RNAi screen in the dorsal spinal cord interneurons, including the commissural neurons. We found that the NOVA family of RBPs ...

X chromosome dosage compensation in Drosophila requires chromosome-wide coordination of gene activation. The male-specific-lethal dosage compensation complex (DCC) identifies X chromosomal High Affinity Sites (HAS) from which it boosts transcription. A sub-class of HAS, PionX sites, represent first contacts on the X. Here, we explored the chromosomal interactions of representative PionX sites b...

[1] We use five years of data from the Atmospheric Infrared Sounder (AIRS) to develop a correlation between the frequency of Deep Convective Clouds (DCC) and the zonal mean tropical surface temperature. AIRS data show that the frequency of DCC in the tropical oceans is very temperature sensitive, increasing 45% per 1 K increase of the zonal mean surface temperature. The combination of the sensi...