Human immunodeficiency virus type 1 nucleocapsid protein is a major structural component of the virion core and a key factor involved in proviral DNA synthesis and virus formation. 2,2'-Dithiobenzamides (DIBA-1) and related compounds that are inhibitors of NCp7 are thought to eject zinc ions from NCp7 zinc fingers, inhibiting the maturation of virion proteins. Here, we show that the presence of...

A rapid and specific dot-enzyme immunoassay (DIBA) using monoclonal antibody was introduced for detection of Trichomonas vaginalis antigen in vaginal and urethral materials. The results of DIBA were compared with culture findings of the parasite in 245 female patients. Taking culture as the reference method, DIBA had a sensitivity of 92% and a specificity of 93%. The predictive value of a posit...

In search for selective ligands for the muscarinic acetylcholine receptor (MR) subtype M2, the dimeric ligand approach, that is combining two pharmacophores in one and the same molecule, was pursued. Different types (agonists, antagonists, orthosteric, and allosteric) of monomeric MR ligands were combined by various linkers with a dibenzodiazepinone-type MR antagonist, affording five types of h...

New Voltage Differencing Differential Input Buffered Amplifier (VD-DIBA) based lossless grounded and floating inductance simulation circuits have been proposed. The proposed grounded simulated inductance circuit employs a single VD-DIBA, one floating resistance and one grounded capacitor. The floating simulated inductance (FI) circuits employ two VD-DIBAs with two passive components (one floati...

By changing the N-donor groups of benzonitrile-based reactants, three novel isopolymolybdate-based compounds, [Cu(DBIBA)3][δ-HMo8O26] (1), [Cu(H2O)(DIBA)(DIBAH)(γ-HMo8O26)]·2H2O (2), and [CuI(DTBA)(Mo2O6)] (3) (HDBIBA = 3,5-di(benzoimidazol-1-yl)benzoic acid, HDIBA = 3,5-di(1H-imidazol-1-yl)benzoic acid and HDTBA = 3,5-di(1,2,4-triazol-1-yl)benzoic acid) were synthesized, in which the benzene c...

background: the witches’ broom disease of lime caused by candidatus phytoplasma aurantifolia, is the most devastating disease of acidian lime in the southern parts of iran. objectives: at present, no effient method has been developed for controlling the disease, therefore quarantine approaches such as early detection and subsequent eradication of infected trees is very important. toward this ...

Contact with the soil, fomites or hands contaminated with the animals’ feces favors accidental human infection either through ingestion of Toxocara canis embryonic eggs, resulting in Visceral Larva Migrans (VLM) syndrome (Coelho et al., 2001), or through percutaneous penetration of Ancylostoma caninum and Ancylostoma braziliense infective larvae, causing Cutaneous Larva Migrans (CLM) Syndrome (...

(a) We are grateful for comments, in particular, from Willem Buiter, Matt Canzoneri, Behzad Diba and Patrick O'Brien and from seminar participants at the Economic History Society Conference, the Money Macro and Finance Conference, Birkbeck College, Reading University and the Bank of England. We would also like to thank two anonymous referees for much constructive criticism. All remaining errors...

The usefulness of a new voltage-sensitive fluorescent dye, the membrane permeant negatively charged oxonol dye diBA-C4-(3)-, was evaluated by measuring the membrane potentials of BICR/M1R-k and L cells with glass microelectrodes and simultaneously recording the fluorescence of the stained cells. The membrane potential of BICR/M1R-k cells was varied between -25 mV and -90 mV by changing the bica...